Cholestenoic acid

Cholestenoic acid is a lipid of Sterol Lipids (ST) class. Cholestenoic acid is associated with abnormalities such as Infection. The involved functions are known as Ligand Binding, Signal Pathways and Stereochemistry. Cholestenoic acid often locates in Blood. The associated genes with Cholestenoic acid are NCOA2 gene and P4HTM gene. The related lipids are cholestenoic acid and Sterols.

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Introduction

To understand associated biological information of Cholestenoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Cholestenoic acid?

Cholestenoic acid is suspected in Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Cholestenoic acid

MeSH term MeSH ID Detail
Xanthomatosis, Cerebrotendinous D019294 14 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Cholestenoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Cholestenoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Cholestenoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Cholestenoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Cholestenoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Cholestenoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Cholestenoic acid

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Authors Title Published Journal PubMed Link
Rodriguez CR et al. Fluorinated oxysterol analogues: Synthesis, molecular modelling and LXRβ activity. 2017 J. Steroid Biochem. Mol. Biol. pmid:27452335
Griffiths WJ et al. Charge-tagging liquid chromatography-mass spectrometry methodology targeting oxysterol diastereoisomers. 2017 Chem. Phys. Lipids pmid:28411018
Crick PJ et al. The oxysterol and cholestenoic acid profile of mouse cerebrospinal fluid. 2015 Steroids pmid:25759118
Theofilopoulos S et al. Cholestenoic acids regulate motor neuron survival via liver X receptors. 2014 J. Clin. Invest. pmid:25271621
Griffiths WJ et al. Analytical strategies for characterization of oxysterol lipidomes: liver X receptor ligands in plasma. 2013 Free Radic. Biol. Med. pmid:22846477
Ermolovich YV et al. 1,4-Chirality transfer via the ester enolate Claisen rearrangements in the preparation of (25R)- and (25S)-cholestenoic acids. 2013 Steroids pmid:23583600
Fang CS et al. Clinical significance of serum lipids in idiopathic pulmonary alveolar proteinosis. 2012 Lipids Health Dis pmid:22252101
Zhi X et al. Structural conservation of ligand binding reveals a bile acid-like signaling pathway in nematodes. 2012 J. Biol. Chem. pmid:22170062
Tian X et al. Impaired lipid metabolism in idiopathic pulmonary alveolar proteinosis. 2011 Lipids Health Dis pmid:21486485
Faure AJ et al. Investigating the effect of paralogs on microarray gene-set analysis. 2011 BMC Bioinformatics pmid:21261946
Mast N et al. Cholestenoic Acid is an important elimination product of cholesterol in the retina: comparison of retinal cholesterol metabolism with that in the brain. 2011 Invest. Ophthalmol. Vis. Sci. pmid:20881306
Liao WL et al. Quantification of cholesterol-metabolizing P450s CYP27A1 and CYP46A1 in neural tissues reveals a lack of enzyme-product correlations in human retina but not human brain. 2011 J. Proteome Res. pmid:21049985
Douda DN et al. SP-D counteracts GM-CSF-mediated increase of granuloma formation by alveolar macrophages in lysinuric protein intolerance. 2009 Orphanet J Rare Dis pmid:20030831
Martin R et al. Synthesis and biological activity of the (25R)-cholesten-26-oic acids--ligands for the hormonal receptor DAF-12 in Caenorhabditis elegans. 2009 Org. Biomol. Chem. pmid:19225674
Martin R et al. Stereoselective synthesis of the hormonally active (25S)-delta7-dafachronic acid, (25S)-Delta4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid. 2008 Org. Biomol. Chem. pmid:19005586
Held JM et al. DAF-12-dependent rescue of dauer formation in Caenorhabditis elegans by (25S)-cholestenoic acid. 2006 Aging Cell pmid:16913876
Babiker A et al. Patients with atherosclerosis may have increased circulating levels of 27-hydroxycholesterol and cholestenoic acid. 2005 Scand. J. Clin. Lab. Invest. pmid:16081359
Meaney S et al. Serum cholestenoic acid as a potential marker of pulmonary cholesterol homeostasis: increased levels in patients with pulmonary alveolar proteinosis. 2004 J. Lipid Res. pmid:15466366
Jabara S et al. Stromal cells of the human postmenopausal ovary display a distinctive biochemical and molecular phenotype. 2003 J. Clin. Endocrinol. Metab. pmid:12519894
Hansson M et al. Marked induction of sterol 27-hydroxylase activity and mRNA levels during differentiation of human cultured monocytes into macrophages. 2003 Biochim. Biophys. Acta pmid:12581873
Fu X et al. 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells. 2001 J. Biol. Chem. pmid:11504730
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