7alpha,12alpha-dihydroxy-4-cholesten-3-one

7alpha,12alpha-dihydroxy-4-cholesten-3-one is a lipid of Sterol Lipids (ST) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 10 references associated with 7alpha,12alpha-dihydroxy-4-cholesten-3-one in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 7alpha,12alpha-dihydroxy-4-cholesten-3-one

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 7alpha,12alpha-dihydroxy-4-cholesten-3-one

MeSH term MeSH ID Detail
Xanthomatosis, Cerebrotendinous D019294 14 associated lipids
Total 1

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 7alpha,12alpha-dihydroxy-4-cholesten-3-one

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Total 6
Authors Title Published Journal PubMed Link
Ogawa S et al. An efficient synthesis of 7α,12α-dihydroxy-4-cholesten-3-one and its biological precursor 7α-hydroxy-4-cholesten-3-one: Key intermediates in bile acid biosynthesis. 2013 Steroids pmid:23707572
Faucher F et al. The crystal structure of human Delta4-3-ketosteroid 5beta-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism. 2008 Biochemistry pmid:18624455
Honda A et al. Differences in hepatic levels of intermediates in bile acid biosynthesis between Cyp27(-/-) mice and CTX. 2001 J. Lipid Res. pmid:11181760
Björkhem I et al. Assay of intermediates in bile acid biosynthesis using isotope dilution--mass spectrometry: hepatic levels in the normal state and in cerebrotendinous xanthomatosis. 1981 J. Lipid Res. pmid:7017048
pmid:
pmid:19075558