7alpha-Hydroxy-4-cholesten-3-one

7alpha-hydroxy-4-cholesten-3-one is a lipid of Sterol Lipids (ST) class. The related lipids are Steroids and Cholestenones.

Cross Reference

Introduction

To understand associated biological information of 7alpha-Hydroxy-4-cholesten-3-one, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 7alpha-Hydroxy-4-cholesten-3-one

MeSH term MeSH ID Detail
Cholestasis D002779 23 associated lipids
Xanthomatosis, Cerebrotendinous D019294 14 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with 7alpha-Hydroxy-4-cholesten-3-one

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

What functions are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

What lipids are associated with 7alpha-Hydroxy-4-cholesten-3-one?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 7alpha-Hydroxy-4-cholesten-3-one

Download all related citations
Per page 10 20 50 100 | Total 146
Authors Title Published Journal PubMed Link
Donato LJ et al. Description of analytical method and clinical utility of measuring serum 7-alpha-hydroxy-4-cholesten-3-one (7aC4) by mass spectrometry. 2018 Clin. Biochem. pmid:29051033
Othman RA et al. Thyroid Hormone Status in Sitosterolemia Is Modified by Ezetimibe. 2017 J. Pediatr. pmid:28625503
Mast N et al. Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum. 2017 J. Biol. Chem. pmid:28190002
Wang Y et al. Barley β-glucan reduces blood cholesterol levels via interrupting bile acid metabolism. 2017 Br. J. Nutr. pmid:29115200
Zweers SJ et al. Prolonged fibroblast growth factor 19 response in patients with primary sclerosing cholangitis after an oral chenodeoxycholic acid challenge. 2017 Hepatol Int pmid:27696157
Mignarri A et al. Evaluation of cholesterol metabolism in cerebrotendinous xanthomatosis. 2016 J. Inherit. Metab. Dis. pmid:26153518
Blahová T et al. The effect of colesevelam treatment on bile acid and lipid metabolism and glycemic control in healthy men. 2016 Physiol Res pmid:27539104
Zhang L et al. Impaired Bile Acid Homeostasis in Children with Severe Acute Malnutrition. 2016 PLoS ONE pmid:27163928
Vlachova M et al. Diurnal variation in cholesterol 7α-hydroxylase activity is determined by the -203A>C polymorphism of the CYP7A1 gene. 2016 Croat. Med. J. pmid:27106353
Graffner H et al. The ileal bile acid transporter inhibitor A4250 decreases serum bile acids by interrupting the enterohepatic circulation. 2016 Aliment. Pharmacol. Ther. pmid:26527417
Chen M et al. The rate-determining steps of aldo-keto reductases (AKRs), a study on human steroid 5β-reductase (AKR1D1). 2015 Chem. Biol. Interact. pmid:25500266
Rudling M et al. Specific inhibition of bile acid transport alters plasma lipids and GLP-1. 2015 BMC Cardiovasc Disord pmid:26197999
Camilleri M et al. Effect of colesevelam on faecal bile acids and bowel functions in diarrhoea-predominant irritable bowel syndrome. 2015 Aliment. Pharmacol. Ther. pmid:25594801
Camilleri M et al. Genetic variation in GPBAR1 predisposes to quantitative changes in colonic transit and bile acid excretion. 2014 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:25012842
Vlaardingerbroek H et al. New generation lipid emulsions prevent PNALD in chronic parenterally fed preterm pigs. 2014 J. Lipid Res. pmid:24478031
Luo J et al. A nontumorigenic variant of FGF19 treats cholestatic liver diseases. 2014 Sci Transl Med pmid:25080475
Amano Y et al. Combinational effects of farnesoid X receptor antagonist and statin on plasma lipid levels and low-density lipoprotein clearance in guinea pigs. 2014 Life Sci. pmid:24805868
Bertolotti M et al. Age-associated alterations in cholesterol homeostasis: evidence from a cross-sectional study in a Northern Italy population. 2014 Clin Interv Aging pmid:24669190
Pattni SS et al. Fibroblast growth factor 19 in patients with bile acid diarrhoea: a prospective comparison of FGF19 serum assay and SeHCAT retention. 2013 Aliment. Pharmacol. Ther. pmid:23981126
Hirsova P et al. Cholestatic effect of epigallocatechin gallate in rats is mediated via decreased expression of Mrp2. 2013 Toxicology pmid:23146761