7alpha-Hydroxy-4-cholesten-3-one

7alpha-hydroxy-4-cholesten-3-one is a lipid of Sterol Lipids (ST) class. The related lipids are Steroids and Cholestenones.

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Introduction

To understand associated biological information of 7alpha-Hydroxy-4-cholesten-3-one, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 7alpha-Hydroxy-4-cholesten-3-one

MeSH term MeSH ID Detail
Cholestasis D002779 23 associated lipids
Xanthomatosis, Cerebrotendinous D019294 14 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with 7alpha-Hydroxy-4-cholesten-3-one

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

What functions are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

What lipids are associated with 7alpha-Hydroxy-4-cholesten-3-one?

Related references are published most in these journals:

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What genes are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 7alpha-Hydroxy-4-cholesten-3-one

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Authors Title Published Journal PubMed Link
Donato LJ et al. Description of analytical method and clinical utility of measuring serum 7-alpha-hydroxy-4-cholesten-3-one (7aC4) by mass spectrometry. 2018 Clin. Biochem. pmid:29051033
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Marschall HU et al. Combined rifampicin and ursodeoxycholic acid treatment does not amplify rifampicin effects on hepatic detoxification and transport systems in humans. 2012 Digestion pmid:22964716
Xiang X et al. Gender, but not CYP7A1 or SLCO1B1 polymorphism, affects the fasting plasma concentrations of bile acids in human beings. 2012 Basic Clin. Pharmacol. Toxicol. pmid:21902813
Wong BS et al. Increased bile acid biosynthesis is associated with irritable bowel syndrome with diarrhea. 2012 Clin. Gastroenterol. Hepatol. pmid:22610000
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Yang Q et al. Dietary fish oil increases fat absorption and fecal bile acid content without altering bile acid synthesis in 20-d-old weanling rats following massive ileocecal resection. 2012 Pediatr. Res. pmid:22447320
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Matysik S et al. Monitoring of 7α-hydroxy-4-cholesten-3-one during therapy of cerebrotendinous xanthomatosis: a case report. 2011 Chem. Phys. Lipids pmid:21679699
Matysik S et al. Bile acid signaling after an oral glucose tolerance test. 2011 Chem. Phys. Lipids pmid:21679700
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Wong BS et al. Effects of A3309, an ileal bile acid transporter inhibitor, on colonic transit and symptoms in females with functional constipation. 2011 Am. J. Gastroenterol. pmid:21876564
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DeBarber AE et al. ESI-MS/MS quantification of 7alpha-hydroxy-4-cholesten-3-one facilitates rapid, convenient diagnostic testing for cerebrotendinous xanthomatosis. 2010 Clin. Chim. Acta pmid:19808031
Schreuder TC et al. The hepatic response to FGF19 is impaired in patients with nonalcoholic fatty liver disease and insulin resistance. 2010 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:20093562
Odunsi-Shiyanbade ST et al. Effects of chenodeoxycholate and a bile acid sequestrant, colesevelam, on intestinal transit and bowel function. 2010 Clin. Gastroenterol. Hepatol. pmid:19879973
Björkhem I and Hansson M Cerebrotendinous xanthomatosis: an inborn error in bile acid synthesis with defined mutations but still a challenge. 2010 Biochem. Biophys. Res. Commun. pmid:20494109
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