7alpha-Hydroxy-4-cholesten-3-one

7alpha-hydroxy-4-cholesten-3-one is a lipid of Sterol Lipids (ST) class. The related lipids are Steroids and Cholestenones.

Cross Reference

Introduction

To understand associated biological information of 7alpha-Hydroxy-4-cholesten-3-one, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 7alpha-Hydroxy-4-cholesten-3-one

MeSH term MeSH ID Detail
Cholestasis D002779 23 associated lipids
Xanthomatosis, Cerebrotendinous D019294 14 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with 7alpha-Hydroxy-4-cholesten-3-one

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

What functions are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

What lipids are associated with 7alpha-Hydroxy-4-cholesten-3-one?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 7alpha-Hydroxy-4-cholesten-3-one

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Authors Title Published Journal PubMed Link
Skrede S and Björkhem I Biosynthesis of cholestanol from intestinal 7 alpha-hydroxy-4-cholesten-3-one. 1982 J. Biol. Chem. pmid:7045120
Kase BF et al. In vivo and vitro studies on formation of bile acids in patients with Zellweger syndrome. Evidence that peroxisomes are of importance in the normal biosynthesis of both cholic and chenodeoxycholic acid. 1985 J. Clin. Invest. pmid:4077985
Ogishima T and Okuda K An improved method for assay of cholesterol 7 alpha-hydroxylase activity. 1986 Anal. Biochem. pmid:3799966
Björkhem I et al. Accumulation of 7 alpha-hydroxy-4-cholesten-3-one and cholesta-4,6-dien-3-one in patients with cerebrotendinous xanthomatosis: effect of treatment with chenodeoxycholic acid. 1987 Mar-Apr Hepatology pmid:3557306
Skrede S et al. Hepatic 7 alpha-dehydroxylation of bile acid intermediates, and its significance for the pathogenesis of cerebrotendinous xanthomatosis. 1988 J. Lipid Res. pmid:3367085
Axelson M et al. Levels of 7 alpha-hydroxy-4-cholesten-3-one in plasma reflect rates of bile acid synthesis in man. 1988 FEBS Lett. pmid:3181435
Axelson M et al. Ethanol has an acute effect on bile acid biosynthesis in man. 1991 FEBS Lett. pmid:2015886
Axelson M et al. The plasma level of 7 alpha-hydroxy-4-cholesten-3-one reflects the activity of hepatic cholesterol 7 alpha-hydroxylase in man. 1991 FEBS Lett. pmid:2060639
Ishida H et al. Purification and characterization of 7 alpha-hydroxy-4-cholesten-3-one 12 alpha-hydroxylase. 1992 J. Biol. Chem. pmid:1400444
Eusufzai S et al. Serum 7 alpha-hydroxy-4-cholesten-3-one concentrations in the evaluation of bile acid malabsorption in patients with diarrhoea: correlation to SeHCAT test. 1993 Gut pmid:8504974