7alpha-Hydroxy-4-cholesten-3-one

7alpha-hydroxy-4-cholesten-3-one is a lipid of Sterol Lipids (ST) class. The related lipids are Steroids and Cholestenones.

Cross Reference

Introduction

To understand associated biological information of 7alpha-Hydroxy-4-cholesten-3-one, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 7alpha-Hydroxy-4-cholesten-3-one

MeSH term MeSH ID Detail
Cholestasis D002779 23 associated lipids
Xanthomatosis, Cerebrotendinous D019294 14 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with 7alpha-Hydroxy-4-cholesten-3-one

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

What functions are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

What lipids are associated with 7alpha-Hydroxy-4-cholesten-3-one?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 7alpha-Hydroxy-4-cholesten-3-one?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 7alpha-Hydroxy-4-cholesten-3-one

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Authors Title Published Journal PubMed Link
Xiang X et al. Gender, but not CYP7A1 or SLCO1B1 polymorphism, affects the fasting plasma concentrations of bile acids in human beings. 2012 Basic Clin. Pharmacol. Toxicol. pmid:21902813
Hosseinpour F et al. 25-Hydroxylation of vitamin D3 in primary cultures of pig hepatocytes: evidence for a role of both CYP2D25 and CYP27A1. 2003 Biochem. Biophys. Res. Commun. pmid:12670492
Björkhem I and Hansson M Cerebrotendinous xanthomatosis: an inborn error in bile acid synthesis with defined mutations but still a challenge. 2010 Biochem. Biophys. Res. Commun. pmid:20494109
Jiang ZY et al. Increased NPC1L1 and ACAT2 expression in the jejunal mucosa from Chinese gallstone patients. 2009 Biochem. Biophys. Res. Commun. pmid:19071091
Bernhardsson C et al. 12alpha-hydroxylation of 7alpha-hydroxy-4-cholesten-3-one by a reconstituted system from rat liver microsomes. 1973 Biochem. Biophys. Res. Commun. pmid:4148126
Faucher F et al. The crystal structure of human Delta4-3-ketosteroid 5beta-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism. 2008 Biochemistry pmid:18624455
Matasconi M et al. Pituitary control of cholesterol metabolism in normal and LDL receptor knock-out mice: effects of hypophysectomy and growth hormone treatment. 2005 Biochim. Biophys. Acta pmid:16185916
Andersson U et al. Rabbit liver contains one major sterol 12alpha-hydroxylase with broad substrate specificity. 1998 Biochim. Biophys. Acta pmid:9461256
Matsuzaki Y et al. Selective inhibition of CYP27A1 and of chenodeoxycholic acid synthesis in cholestatic hamster liver. 2002 Biochim. Biophys. Acta pmid:12385778
Rudling M et al. Specific inhibition of bile acid transport alters plasma lipids and GLP-1. 2015 BMC Cardiovasc Disord pmid:26197999