pregnenolone sulfate

Pregnenolone sulfate is a lipid of Sterol Lipids (ST) class. Pregnenolone sulfate is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Transcriptional Activation, Stimulus, Exocytosis and inhibitors. Pregnenolone sulfate often locates in Extracellular, Membrane, Protoplasm, Cell membrane and Cytoplasmic. The associated genes with pregnenolone sulfate are TRPM3 gene, JUN gene, MAPK1 gene, ATF2 gene and Genes, Reporter. The related lipids are Steroids, pregnenolone sulfate, estradiol 17-sulfate, 16-androstene and steroid sulfate.

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Introduction

To understand associated biological information of pregnenolone sulfate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with pregnenolone sulfate?

pregnenolone sulfate is suspected in and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with pregnenolone sulfate

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with pregnenolone sulfate?

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What functions are associated with pregnenolone sulfate?


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What lipids are associated with pregnenolone sulfate?

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What genes are associated with pregnenolone sulfate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with pregnenolone sulfate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with pregnenolone sulfate

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Authors Title Published Journal PubMed Link
Tóth BI et al. Regulation of the transient receptor potential channel TRPM3 by phosphoinositides. 2015 J. Gen. Physiol. pmid:26123194
Wong P et al. Pregnenolone sulfate normalizes schizophrenia-like behaviors in dopamine transporter knockout mice through the AKT/GSK3β pathway. 2015 Transl Psychiatry pmid:25781227
Held K et al. Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:25733887
Brown RL et al. TRPM3 expression in mouse retina. 2015 PLoS ONE pmid:25679224
Lesch A et al. Transient receptor potential melastatin-3 (TRPM3)-induced activation of AP-1 requires Ca2+ ions and the transcription factors c-Jun, ATF2, and ternary complex factor. 2015 Mol. Pharmacol. pmid:25576487
Son GY et al. Hypotonic stress induces RANKL via transient receptor potential melastatin 3 (TRPM3) and vaniloid 4 (TRPV4) in human PDL cells. 2015 J. Dent. Res. pmid:25595364
Smith CC et al. A role for picomolar concentrations of pregnenolone sulfate in synaptic activity-dependent Ca2+ signaling and CREB activation. 2014 Mol. Pharmacol. pmid:25057049
Schuler G et al. Free and sulfated steroids secretion in postpubertal boars (Sus scrofa domestica). 2014 Reproduction pmid:24961601
Lesch A et al. Activation and inhibition of transient receptor potential TRPM3-induced gene transcription. 2014 Br. J. Pharmacol. pmid:24895737
El Bitar F et al. Neuroprotection by the synthetic neurosteroid enantiomers ent-PREGS and ent-DHEAS against Aβ₂₅₋₃₅ peptide-induced toxicity in vitro and in vivo in mice. 2014 Psychopharmacology (Berl.) pmid:24481566