Glycocholic Acid

Glycocholic acid is a lipid of Sterol Lipids (ST) class. Glycocholic acid is associated with abnormalities such as Gastric ulcer, Kissing ulcers, Liver Cirrhosis, Hepatitis and Wiskott-Aldrich Syndrome. The involved functions are known as Stimulus, Ulcer, Pressure- physical agent, Regulation and Uptake. Glycocholic acid often locates in Mucous Membrane, Gastric mucosa, Hepatic and Blood. The associated genes with Glycocholic Acid are AGXT gene, FABP6 gene and glycine methyl ester hydrochloride. The related lipids are Sterols.

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Introduction

To understand associated biological information of Glycocholic Acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Glycocholic Acid?

Glycocholic Acid is suspected in Liver Cirrhosis, Hepatitis, Gastric ulcer, Kissing ulcers, Cholestasis and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Glycocholic Acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Glycocholic Acid?

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What functions are associated with Glycocholic Acid?


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What lipids are associated with Glycocholic Acid?

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What genes are associated with Glycocholic Acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Glycocholic Acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Glycocholic Acid

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Authors Title Published Journal PubMed Link
Zhang A et al. Urinary metabolic profiling identifies a key role for glycocholic acid in human liver cancer by ultra-performance liquid-chromatography coupled with high-definition mass spectrometry. 2013 Clin. Chim. Acta pmid:23313056
Favretto F et al. Ligand binding promiscuity of human liver fatty acid binding protein: structural and dynamic insights from an interaction study with glycocholate and oleate. 2013 Chembiochem pmid:23757005
Mitome H et al. An efficient laboratory-scale preparative method for [1-(13)C]glycocholic acid. 2013 J Labelled Comp Radiopharm pmid:24285191
Hu S et al. Integrity and stability of oral liposomes containing bile salts studied in simulated and ex vivo gastrointestinal media. 2013 Int J Pharm pmid:23089580
Matyja A et al. Telocytes: new insight into the pathogenesis of gallstone disease. 2013 J. Cell. Mol. Med. pmid:23551596
Das N et al. Statistical optimization of insulin-loaded Pluronic F-127 gels for buccal delivery of basal insulin. 2012 May-Jun Pharm Dev Technol pmid:21214425
Ressom HW et al. Utilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis. 2012 Anal. Chim. Acta pmid:22882828
Devkota S et al. Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice. 2012 Nature pmid:22722865
Chen X et al. Bile salts disrupt human esophageal squamous epithelial barrier function by modulating tight junction proteins. 2012 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:22575221
Nicklasson M et al. Expression of colonization factor CS5 of enterotoxigenic Escherichia coli (ETEC) is enhanced in vivo and by the bile component Na glycocholate hydrate. 2012 PLoS ONE pmid:22563407