Tauroursodeoxycholic acid

Tauroursodeoxycholic acid is a lipid of Sterol Lipids (ST) class. Tauroursodeoxycholic acid is associated with abnormalities such as Hyperglycemia, Obesity, Wiskott-Aldrich Syndrome, neurogenic hypertension and Cholestatic liver disease. The involved functions are known as Cell Death, Apoptosis, Homeostasis, Process and mRNA Expression. Tauroursodeoxycholic acid often locates in Body tissue, Endoplasmic Reticulum, Hepatic, Blood and Protoplasm. The associated genes with Tauroursodeoxycholic acid are Homologous Gene and Mutant Proteins. The related lipids are cholanic acid, taurolithocholic acid 3-sulfate, Sterols, 7-dehydrocholesterol and tauromuricholic acid. The related experimental models are Disease model.

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Introduction

To understand associated biological information of Tauroursodeoxycholic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Tauroursodeoxycholic acid?

Tauroursodeoxycholic acid is suspected in Endothelial dysfunction, Hyperglycemia, Obesity, neurogenic hypertension, Cholestatic liver disease, Heart failure and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Tauroursodeoxycholic acid

MeSH term MeSH ID Detail
Hypertension D006973 115 associated lipids
Insulin Resistance D007333 99 associated lipids
Total 2

PubChem Associated disorders and diseases

What pathways are associated with Tauroursodeoxycholic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Tauroursodeoxycholic acid?

Related references are published most in these journals:

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What functions are associated with Tauroursodeoxycholic acid?


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What lipids are associated with Tauroursodeoxycholic acid?

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What genes are associated with Tauroursodeoxycholic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Tauroursodeoxycholic acid?

Disease model

Disease model are used in the study 'Bile Acids Reduce Prion Conversion, Reduce Neuronal Loss, and Prolong Male Survival in Models of Prion Disease.' (Cortez LM et al., 2015).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Tauroursodeoxycholic acid

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Authors Title Published Journal PubMed Link
Wong MK et al. Nicotine Directly Induces Endoplasmic Reticulum Stress Response in Rat Placental Trophoblast Giant Cells. 2016 Toxicol. Sci. pmid:26803847
Keune WJ et al. Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling. 2016 Nat Commun pmid:27075612
Fu J et al. Endoplasmic reticulum stress is involved in 2,4-dichlorophenol-induced hepatotoxicity. 2016 J Toxicol Sci pmid:27853103
Memme JM et al. Chronology of UPR activation in skeletal muscle adaptations to chronic contractile activity. 2016 Am. J. Physiol., Cell Physiol. pmid:27122157
Keestra-Gounder AM et al. NOD1 and NOD2 signalling links ER stress with inflammation. 2016 Nature pmid:27007849
Flodby P et al. The 78-kD Glucose-Regulated Protein Regulates Endoplasmic Reticulum Homeostasis and Distal Epithelial Cell Survival during Lung Development. 2016 Am. J. Respir. Cell Mol. Biol. pmid:26816051
Ding W et al. Involvement of Endoplasmic Reticulum Stress in Uremic Cardiomyopathy: Protective Effects of Tauroursodeoxycholic Acid. 2016 Cell. Physiol. Biochem. pmid:26765262
Hu J et al. Tauroursodeoxycholic acid prevents hearing loss and hair cell death in Cdh23(erl/erl) mice. 2016 Neuroscience pmid:26748055
Yang X et al. Activation of autophagy by unfolded proteins during endoplasmic reticulum stress. 2016 Plant J. pmid:26616142
Elia AE et al. Tauroursodeoxycholic acid in the treatment of patients with amyotrophic lateral sclerosis. 2016 Eur. J. Neurol. pmid:25664595