2-hydroxyglutaric acid

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1586 references associated with 2-hydroxyglutaric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 2-hydroxyglutaric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-hydroxyglutaric acid

MeSH term MeSH ID Detail
Phenylketonurias D010661 7 associated lipids
Canavan Disease D017825 2 associated lipids
Metabolic Diseases D008659 12 associated lipids
Tyrosinemias D020176 2 associated lipids
Hyperoxaluria D006959 3 associated lipids
Total 5

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 2-hydroxyglutaric acid

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Authors Title Published Journal PubMed Link
Choi C et al. Prospective Longitudinal Analysis of 2-Hydroxyglutarate Magnetic Resonance Spectroscopy Identifies Broad Clinical Utility for the Management of Patients With IDH-Mutant Glioma. 2016 J. Clin. Oncol. pmid:28248126
Burr SP et al. Mitochondrial Protein Lipoylation and the 2-Oxoglutarate Dehydrogenase Complex Controls HIF1α Stability in Aerobic Conditions. 2016 Cell Metab. pmid:27923773
Tyrakis PA et al. S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate. 2016 Nature pmid:27798602
Nadtochiy SM et al. Acidic pH Is a Metabolic Switch for 2-Hydroxyglutarate Generation and Signaling. 2016 J. Biol. Chem. pmid:27510037
Flavahan WA et al. Insulator dysfunction and oncogene activation in IDH mutant gliomas. 2016 Nature pmid:26700815
de la Fuente MI et al. Integration of 2-hydroxyglutarate-proton magnetic resonance spectroscopy into clinical practice for disease monitoring in isocitrate dehydrogenase-mutant glioma. 2016 Neuro-oncology pmid:26691210
Emir UE et al. Noninvasive Quantification of 2-Hydroxyglutarate in Human Gliomas with IDH1 and IDH2 Mutations. 2016 Cancer Res. pmid:26669865
Liesenfeld DB et al. Aspirin Reduces Plasma Concentrations of the Oncometabolite 2-Hydroxyglutarate: Results of a Randomized, Double-Blind, Crossover Trial. 2016 Cancer Epidemiol. Biomarkers Prev. pmid:26585118
Andronesi OC et al. Treatment Response Assessment in IDH-Mutant Glioma Patients by Noninvasive 3D Functional Spectroscopic Mapping of 2-Hydroxyglutarate. 2016 Clin. Cancer Res. pmid:26534967
Waitkus MS et al. Isocitrate dehydrogenase mutations in gliomas. 2016 Neuro-oncology pmid:26188014