Nervonic acid is a lipid of Fatty Acyls (FA) class. Nervonic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Metabolic syndrome. The involved functions are known as Inflammation, Insulin Resistance and Synthesis. Nervonic acid often locates in peroxisomal part and peroxisome. The associated genes with Nervonic acid are ACOX1 gene, TNF gene and CCL2 gene. The related lipids are nervonic acid, Fatty Acids, Unsaturated, palmitoleic acid and Sphingolipids.
To understand associated biological information of Nervonic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Nervonic acid is suspected in Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Nervonic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adrenoleukodystrophy | D000326 | 29 associated lipids |
| Zellweger Syndrome | D015211 | 39 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
| Premature Birth | D047928 | 6 associated lipids |
| Inert Gas Narcosis | D007222 | 1 associated lipids |
| Cleft Lip | D002971 | 8 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Medema S et al. | Levels of Red Blood Cell Fatty Acids in Patients With Psychosis, Their Unaffected Siblings, and Healthy Controls. | 2016 | Schizophr Bull | pmid:26385764 |
| Pickens CA et al. | Plasma phospholipids, non-esterified plasma polyunsaturated fatty acids and oxylipids are associated with BMI. | 2015 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:25559239 |
| Huai D et al. | Combinatorial Effects of Fatty Acid Elongase Enzymes on Nervonic Acid Production in Camelina sativa. | 2015 | PLoS ONE | pmid:26121034 |
| Umemoto H et al. | Fermentative production of nervonic acid by Mortierella capitata RD000969. | 2014 | J Oleo Sci | pmid:24919474 |
| Yamazaki Y et al. | Proportion of nervonic acid in serum lipids is associated with serum plasmalogen levels and metabolic syndrome. | 2014 | J Oleo Sci | pmid:24770479 |
| Peters BD et al. | Polyunsaturated fatty acid concentration predicts myelin integrity in early-phase psychosis. | 2013 | Schizophr Bull | pmid:22927668 |
| Ntoumani E et al. | Nervonic acid is much lower in donor milk than in milk from mothers delivering premature infants--of neglected importance? | 2013 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:23870193 |
| Yuan H et al. | [Effect of docosahexaenoic acid and nervonic acid on the damage of learning and memory abilities in rats induced by 1-bromopropane]. | 2013 | Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi | pmid:24370287 |
| Snigdha S et al. | Effects of diet and behavioral enrichment on free fatty acids in the aged canine brain. | 2012 | Neuroscience | pmid:22183056 |
| Shearer GC et al. | Plasma fatty acids in chronic kidney disease: nervonic acid predicts mortality. | 2012 | J Ren Nutr | pmid:21775161 |