2,5-hexanedione

2,5-hexanedione is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 1519 references associated with 2,5-hexanedione in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 2,5-hexanedione

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2,5-hexanedione

MeSH term MeSH ID Detail
Neurotoxicity Syndromes D020258 34 associated lipids
Gait Disorders, Neurologic D020233 3 associated lipids
Retrograde Degeneration D012183 4 associated lipids
Optic Atrophy, Hereditary, Leber D029242 4 associated lipids
Per page 10 20 50 | Total 24

NCBI Entrez Crosslinks

All references with 2,5-hexanedione

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Per page 10 20 50 100 | Total 418
Authors Title Published Journal PubMed Link
Wang Z et al. 2,5-hexanedione downregulates nerve growth factor and induces neuron apoptosis in the spinal cord of rats via inhibition of the PI3K/Akt signaling pathway. 2017 PLoS ONE pmid:28654704
Li S et al. Taurine inhibits 2,5-hexanedione-induced oxidative stress and mitochondria-dependent apoptosis in PC12 cells. 2017 Ind Health pmid:27840369
Dere E et al. From the Cover: Sperm Molecular Biomarkers Are Sensitive Indicators of Testicular Injury following Subchronic Model Toxicant Exposure. 2016 Toxicol. Sci. pmid:27466211
Liu S et al. 2,5-hexanedione induced apoptosis of rat bone marrow mesenchymal stem cells by reactive oxygen species. 2016 J Occup Health pmid:27010086
Ma SX et al. Impaired expression of neuronal nitric oxide synthase in the gracile nucleus is involved in neuropathic changes in Zucker Diabetic Fatty rats with and without 2,5-hexanedione intoxication. 2016 Neurosci. Res. pmid:26519861
Chen R et al. 2,5-hexanedione induced apoptosis in mesenchymal stem cells from rat bone marrow via mitochondria-dependent caspase-3 pathway. 2015 Ind Health pmid:25739802
LoPachin RM and Gavin T Toxic neuropathies: Mechanistic insights based on a chemical perspective. 2015 Neurosci. Lett. pmid:25218479
Gagnaire F and Boucard S Olfactory mucosal necrosis in rats following acute intraperitoneal administration of 1,2-diethylbenzene, 1,2-diacetylbenzene and 2,5-hexanedione. 2014 Neurotoxicology pmid:24373906
Catlin NR et al. The stage-specific testicular germ cell apoptotic response to low-dose X-irradiation and 2,5-hexanedione combined exposure. I: Validation of the laser capture microdissection method for qRT-PCR array application. 2014 Toxicol Pathol pmid:24717900
Catlin NR et al. The stage-specific testicular germ cell apoptotic response to low-dose radiation and 2,5-hexanedione combined exposure. II: qRT-PCR array analysis reveals dose dependent adaptive alterations in the apoptotic pathway. 2014 Toxicol Pathol pmid:24670816