1,2-Dioleoyl-sn-glycerol

1,2-Dioleoyl-sn-glycerol is a lipid of Glycerolipids (GL) class. 1,2-dioleoyl-sn-glycerol is associated with abnormalities such as SAPOSIN D (disease) and Exanthema. The involved functions are known as Energy Transfer, Increased Sensitivy, Chelating Activity [MoA], protein kinase C activity and Phosphorylation. 1,2-dioleoyl-sn-glycerol often locates in vesicle, Tissue membrane, Membrane, viral nucleocapsid location and Protoplasm. The associated genes with 1,2-Dioleoyl-sn-glycerol are SIGLEC12 gene, Genome, RNF7 gene, FANCL gene and TNFRSF11B gene. The related lipids are Unilamellar Vesicles, diolein, Phosphatidylserines, Fatty Acids and monoolein.

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Introduction

To understand associated biological information of 1,2-Dioleoyl-sn-glycerol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 1,2-Dioleoyl-sn-glycerol?

1,2-Dioleoyl-sn-glycerol is suspected in SAPOSIN D (disease), Exanthema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 1,2-Dioleoyl-sn-glycerol

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with 1,2-Dioleoyl-sn-glycerol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 1,2-Dioleoyl-sn-glycerol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 1,2-Dioleoyl-sn-glycerol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 1,2-Dioleoyl-sn-glycerol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 1,2-Dioleoyl-sn-glycerol

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Authors Title Published Journal PubMed Link
Sharkey NA and Blumberg PM Kinetic evidence that 1,2-diolein inhibits phorbol ester binding to protein kinase C via a competitive mechanism. 1985 Biochem. Biophys. Res. Commun. pmid:3936500
Lin T The role of calcium/phospholipid-dependent protein kinase in Leydig cell steroidogenesis. 1985 Endocrinology pmid:2988910
Omri B and Pavlovic-Hournac M Protein kinase C activity in experimentally developed and regressed rat thyroid goitres. 1985 Mol. Cell. Endocrinol. pmid:3159607
Friedman Y et al. Diacylglycerol-activated, calcium/phospholipid-dependent protein kinase (protein kinase C) activity in bovine thyroid. 1985 Biochem. Biophys. Res. Commun. pmid:3161511
Okazaki T et al. The identification and characterization of protein kinase C activity in fetal membranes. 1984 Arch. Biochem. Biophys. pmid:6230994
Nishikawa M et al. Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase. 1984 J. Biol. Chem. pmid:6235218
Rando RR and Young N The stereospecific activation of protein kinase C. 1984 Biochem. Biophys. Res. Commun. pmid:6235812
Kapoor CL and Chader GJ Endogenous phosphorylation of retinal photoreceptor outer segment proteins by calcium phospholipid-dependent protein kinase. 1984 Biochem. Biophys. Res. Commun. pmid:6236809
Hubinont CJ et al. Activation of protein kinase C by a tumor-promoting phorbol ester in pancreatic islets. 1984 FEBS Lett. pmid:6327381
Ganong BR and Bell RM Transmembrane movement of phosphatidylglycerol and diacylglycerol sulfhydryl analogues. 1984 Biochemistry pmid:6498172