17-octadecynoic acid is a lipid of Fatty Acyls (FA) class. 17-octadecynoic acid is associated with abnormalities such as Renal tubular disorder, Hypertensive disease, abnormal fragmented structure, Blood Clot and Subarachnoid Hemorrhage. The involved functions are known as Hypoxia, Pathological Dilatation, Anabolism, Biochemical Pathway and Stimulus. 17-octadecynoic acid often locates in Endothelium, Muscle, Protoplasm, Microsomes and Membrane. The associated genes with 17-octadecynoic acid are P4HTM gene, EDNRA gene, Gene Family, IMPACT gene and PPP1R1A gene. The related lipids are 17-octadecynoic acid, Fatty Acids, 1-oleoyl-2-acetoyl-sn-glycerol and fatty acid analog.
To understand associated biological information of 17-octadecynoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
17-octadecynoic acid is suspected in Hypertensive disease, Renal tubular disorder, Blood Clot, Subarachnoid Hemorrhage, Renal vascular disorder and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 17-octadecynoic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Hyperthyroidism | D006980 | 12 associated lipids |
| Cicatrix | D002921 | 9 associated lipids |
| Glioblastoma | D005909 | 27 associated lipids |
| Corneal Neovascularization | D016510 | 8 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sanders RJ et al. | Omega-oxidation of very long-chain fatty acids in human liver microsomes. Implications for X-linked adrenoleukodystrophy. | 2006 | J. Biol. Chem. | pmid:16547005 |
| Campbell WB et al. | Regulation of potassium channels in coronary smooth muscle by adenoviral expression of cytochrome P-450 epoxygenase. | 2006 | Am. J. Physiol. Heart Circ. Physiol. | pmid:16143653 |
| Krummen S et al. | ROS-sensitive cytochrome P450 activity maintains endothelial dilatation in ageing but is transitory in dyslipidaemic mice. | 2006 | Br. J. Pharmacol. | pmid:16474414 |
| Komen JC and Wanders RJ | Identification of the cytochrome P450 enzymes responsible for the omega-hydroxylation of phytanic acid. | 2006 | FEBS Lett. | pmid:16782090 |
| Loyaga-Rendon RY et al. | Mediators involved in decreasing peripheral vascular resistance with carbachol in the rat hind limb perfusion model. | 2005 | J. Pharmacol. Sci. | pmid:16006739 |
| Li F and Malik KU | Angiotensin II-induced Akt activation is mediated by metabolites of arachidonic acid generated by CaMKII-stimulated Ca2(+)-dependent phospholipase A2. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15637121 |
| Wang X et al. | Redundant signaling mechanisms contribute to the vasodilatory response of the afferent arteriole to proteinase-activated receptor-2. | 2005 | Am. J. Physiol. Renal Physiol. | pmid:15328067 |
| Hatoum OA et al. | Role of hydrogen peroxide in ACh-induced dilation of human submucosal intestinal microvessels. | 2005 | Am. J. Physiol. Heart Circ. Physiol. | pmid:15345486 |
| Sanders RJ et al. | Evidence for two enzymatic pathways for omega-oxidation of docosanoic acid in rat liver microsomes. | 2005 | J. Lipid Res. | pmid:15716582 |
| Mezentsev A et al. | Transfection of cytochrome P4504B1 into the cornea increases angiogenic activity of the limbal vessels. | 2005 | J. Pharmacol. Exp. Ther. | pmid:16009741 |