Disease MeSH term: Niemann-Pick Diseases

Possible associated with:

Structure name description Reference count
25-Hydroxycholesterol 25-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 25-hydroxycholesterol is associated with abnormalities such as Hereditary Diseases, Atherosclerosis, Fatty Liver, Infection and Exanthema. The involved functions are known as Binding (Molecular Function), cholesterol binding, sterol binding, oxysterol binding and Regulation. 25-hydroxycholesterol often locates in Membrane, Golgi membrane, Cellular Membrane, Cytoplasmic matrix and Golgi Apparatus. The associated genes with 25-Hydroxycholesterol are PTPN7 gene, OSBP gene, N-glycylalanine, SCAP gene and TSPO gene. The related lipids are 25-hydroxycholesterol, Sterols, Hydroxycholesterols, 27-hydroxycholesterol and Steroids. The related experimental models are Knock-out. 757
Mevalonic acid Mevalonic acid is a lipid of Fatty Acyls (FA) class. 1437
Cholecalciferol Cholecalciferol is a lipid of Sterol Lipids (ST) class. Cholecalciferol is associated with abnormalities such as Vitamin D Deficiency. The involved functions are known as cholesterol desmolase activity and Cytokinesis of the fertilized ovum. Cholecalciferol often locates in Mitochondria, Integumentary system, Body tissue, Entire gastrointestinal tract and Blood. The related lipids are 7-dehydrocholesterol, zymosterol and isotachysterol. 1473
(e,e,e,e)-squalene (e,e,e,e)-squalene is a lipid of Fatty Acyls (FA) class. (e,e,e,e)-squalene is associated with abnormalities such as Hypercholesterolemia and Cataract. The involved functions are known as Process, metaplastic cell transformation, Protein Overexpression, Anabolism and Biosynthetic Pathways. (e,e,e,e)-squalene often locates in Membrane, Protoplasm, Plasma membrane, Tissue membrane and Back. The associated genes with (e,e,e,e)-squalene are Genome, IMPACT gene, GAPDH gene, GTF2I gene and Chromatin. The related lipids are Membrane Lipids, cycloartenol, Sterols, Fatty Acids and Nonesterified Fatty Acids. 1766
Sphingosine 1-phosphate Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis. 2005
1,2-Dioleoyl-sn-Glycero-3-Phosphocholine 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model. 3428
Taurocholic acid Taurocholic acid is a lipid of Sterol Lipids (ST) class. Taurocholic acid is associated with abnormalities such as Cholestasis, Cholestatic liver disease, Exanthema, Hepatitis and Fibrosis, Liver. The involved functions are known as Uptake, Metabolic Inhibition, Drug Interactions, inhibitors and Excretory function. Taurocholic acid often locates in Hepatic, Plasma membrane, Blood, Membrane and Endothelium. The associated genes with Taurocholic acid are SLC10A1 gene, SLCO1B1 gene, SLC10A2 gene, P4HTM gene and Polypeptides. The related lipids are Steroids, Sterols, Lipopolysaccharides, 7-dehydrocholesterol and cholanic acid. 3446
Lysophosphatidylcholine Lysophosphatidylcholine is a lipid of Glycerophospholipids (GP) class. Lysophosphatidylcholine is associated with abnormalities such as Ischemia, Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Fatty Liver and Atherosclerosis. The involved functions are known as Inflammation, antagonists, Signal Transduction, Signal Pathways and Saturated. Lysophosphatidylcholine often locates in Body tissue, Head, integral to membrane, Membrane and Extracellular. The associated genes with Lysophosphatidylcholine are RHOA gene, Homologous Gene, GPR4 gene, GPR68 gene and TRPV2 gene. The related lipids are Nonesterified Fatty Acids, lysophosphatidylethanolamine, Lysophosphatidylcholines, Phosphatidylserines and 25-hydroxycholesterol. The related experimental models are Knock-out and Disease model. 4395
3-epivitamin D3 / 3-epicholecalciferol 3-epivitamin d3 / 3-epicholecalciferol is a lipid of Sterol Lipids (ST) class. 3-epivitamin d3 / 3-epicholecalciferol is associated with abnormalities such as Vitamin D Deficiency. The involved functions are known as Cell Proliferation, cholesterol desmolase activity and Cytokinesis of the fertilized ovum. 3-epivitamin d3 / 3-epicholecalciferol often locates in Blood, Body tissue, Mitochondria, Entire gastrointestinal tract and Integumentary system. The related lipids are 7-dehydrocholesterol, Dehydrocholesterols, zymosterol and isotachysterol. 5598
DHA Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental. 11054
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