|
Xanthohumol |
Xanthohumol is a lipid of Polyketides (PK) class. Xanthohumol is associated with abnormalities such as Endometriosis, site unspecified, Cyst, peritoneal lesion, Proliferative inflammation and furuncle. The involved functions are known as Cell Proliferation, Signal Transduction, Pathologic Neovascularization, Adverse effects and Proliferation (morphologic abnormality). Xanthohumol often locates in peritoneal, Mesentery, Membrane, Tissue specimen from uterus and Cell Nucleus. The associated genes with Xanthohumol are PI3 gene, KEAP1 gene, SLC33A1 gene, BCR-ABL Fusion Gene and BIRC5 gene. The related lipids are Fatty Acids and Palmitates. The related experimental models are Knock-out. |
465 |
|
rottlerin |
Rottlerin is a lipid of Polyketides (PK) class. Rottlerin is associated with abnormalities such as PARAGANGLIOMAS 2, Hyperostosis, Diffuse Idiopathic Skeletal, Virus Diseases, Perisylvian syndrome and Autoimmune disease (systemic) NOS. The involved functions are known as Apoptosis, Regulation, Signal Transduction, inhibitors and Proteasome Inhibitors [MoA]. Rottlerin often locates in Clone, Membrane, Body tissue, Plasma membrane and soluble. The associated genes with Rottlerin are XIAP gene, GAPDH gene, ICAM1 gene, P4HTM gene and TNFSF10 gene. The related lipids are Promega, Fatty Acids, Sphingolipids, Lipopolysaccharides and Saponin. The related experimental models are Mouse Model, Xenograft Model and Cancer Model. |
1198 |
|
phloretin |
phloretin is a lipid of Polyketides (PK) class. Phloretin is associated with abnormalities such as Atherosclerosis, Diabetes Mellitus, Non-Insulin-Dependent, Alkalemia, Renal tubular disorder and pathologic fistula. The involved functions are known as Anabolism, glycosyltransferase activity, Biosynthetic Pathways, Localized desquamation and Biological Processes. Phloretin often locates in soluble, BL21, Cytoplasmic, Extracellular and Cytoplasm. The associated genes with phloretin are Homologous Gene, CD36 gene, Candidate Disease Gene, SLC33A1 gene and PAK1IP1 gene. The related lipids are Liposomes, Palmitates, Fatty Acids, Sterols and 6-ketocholestanol. The related experimental models are Knock-out. |
2367 |
|
naringenin |
naringenin is a lipid of Polyketides (PK) class. Naringenin is associated with abnormalities such as Dehydration, Papillon-Lefevre Disease, BOSLEY-SALIH-ALORAINY SYNDROME, Cardiovascular Diseases and Atherosclerosis. The involved functions are known as Pigmentation, Biosynthetic Pathways, metaplastic cell transformation, 4-coumarate-CoA ligase activity and Pigment. Naringenin often locates in Body tissue, Cell Wall, Membrane, Cytoplasmic matrix and Tissue membrane. The associated genes with naringenin are Genome, Genes, Regulator, Alleles, Homologous Gene and SPEN gene. The related lipids are Fatty Acids, Total cholesterol, Lipopolysaccharides, Oleates and Cholesterol, Dietary. The related experimental models are Knock-out and Mouse Model. |
2420 |
|
Poncirin |
Poncirin is a lipid of Polyketides (PK) class. |
53 |
|
Isosakuranetin |
Isosakuranetin is a lipid of Polyketides (PK) class. |
49 |
|
Pterosupin |
Pterosupin is a lipid of Polyketides (PK) class. |
8 |
|
ERIODICTYOL |
Eriodictyol is a lipid of Polyketides (PK) class. Eriodictyol is associated with abnormalities such as Hyperostosis, Diffuse Idiopathic Skeletal, Macular degeneration, Consumption-archaic term for TB, Retinal Diseases and PARAGANGLIOMAS 4. The involved functions are known as glutathione biosynthetic process, Cytoprotection, Oxidants, protein expression and Cell Survival. Eriodictyol often locates in Cytoplasmic matrix, Protoplasm, Cytoplasmic, Cell Fraction and Back. The associated genes with Eriodictyol are NQO, HMOX1 gene, IMPACT gene, RPS6KA3 gene and GDNF gene. |
311 |
|
hesperetin |
Hesperetin is a lipid of Polyketides (PK) class. Hesperetin is associated with abnormalities such as Corn of toe, Ischemia, Osteoporosis, Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as conjugation, inhibitors, Process, mRNA Expression and Adjudication. Hesperetin often locates in Entire intestinal epithelium, Protoplasm, Membrane, Shoulder and Back. The associated genes with Hesperetin are ABCG2 gene, ABCC2 gene, FATE1 gene, ABCB1 gene and P-glycoprotein 2. |
801 |
|
Liquiritigenin |
Liquiritigenin is a lipid of Polyketides (PK) class. Liquiritigenin is associated with abnormalities such as POSTMENOPAUSAL SYNDROME, Hyperostosis, Diffuse Idiopathic Skeletal, PARAGANGLIOMAS 2, Wiskott-Aldrich Syndrome and Alzheimer's Disease. The involved functions are known as Heterodimerization, Transcription, Genetic, Ligand Binding, Transcriptional Activation and Anabolism. Liquiritigenin often locates in Membrane, Blood, Microsomes, Liver, Microsomes and Body tissue. The associated genes with Liquiritigenin are Candidate Disease Gene, IMPACT gene, TNFSF10 gene, SLC33A1 gene and P4HTM gene. The related lipids are Lipopolysaccharides, pregnenolone sulfate and FuGene. The related experimental models are Xenograft Model. |
313 |
|
NSC5548 |
NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol. |
283 |
|
LMPK12140236 |
LMPK12140236 is a lipid of Polyketides (PK) class. |
8 |
|
hesperidin |
(2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxyhexopyranosyl)hexopyranoside is a lipid of Polyketides (PK) class. (2s)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2h-chromen-7-yl 6-o-(6-deoxyhexopyranosyl)hexopyranoside is associated with abnormalities such as Osteoporosis, Postmenopausal, estrogen deficiency, Chronic venous insufficiency, Neurodegenerative Disorders and Cerebrovascular accident. The involved functions are known as Sweetening Agents, Vmax, enzyme activity, Fermentation and Regulation. (2s)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2h-chromen-7-yl 6-o-(6-deoxyhexopyranosyl)hexopyranoside often locates in Entire gastrointestinal tract, soluble, Entire bony skeleton, Trabecular substance of bone and Blood. The associated genes with (2S)-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-3,4-dihydro-2H-chromen-7-yl 6-O-(6-deoxyhexopyranosyl)hexopyranoside are MTPN gene, GLUCOSIDASE, STN gene, SLC33A1 gene and GHRL gene. The related lipids are Total cholesterol and blood lipid. The related experimental models are Arthritis, Collagen-Induced. |
1455 |
|
Glycycoumarin |
Glycycoumarin is a lipid of Polyketides (PK) class. Glycycoumarin is associated with abnormalities such as Hypertensive disease and Hyperglycemia. The involved functions are known as Ligand Binding, Peroxisome Proliferator-activated Receptor Activity [MoA] and peroxisome proliferator activated receptor binding. Glycycoumarin often locates in Blood, Mesentery, Adipose tissue and Entire nose, accessory sinus and nasopharynx, CS. |
36 |
|
hypericin |
hypericin is a lipid of Polyketides (PK) class. Hypericin is associated with abnormalities such as Dermatitis, Phototoxic, Dehydration, Photosensitization, Morphologically altered structure and Myocardial Infarction. The involved functions are known as Cell Cycle Checkpoints, Apoptosis, Acetylation, Cell Survival and Caspase Activation. Hypericin often locates in insoluble fraction, Cytoplasmic matrix, Protoplasm, Tissue membrane and Cytoplasm. The associated genes with hypericin are CDC37 gene, HSPA8 gene, RAF1 gene, cyclin H and FK228. The related lipids are Phosphatidylserines. |
1752 |
|
emodin |
emodin is a lipid of Polyketides (PK) class. Emodin is associated with abnormalities such as Infection, Conjunctivitis, Vernal, Stevens-Johnson Syndrome, Conjunctival scar and Allergic Conjunctivitis. The involved functions are known as signaling cascade, Metabolic Inhibition, Cell Death, Phosphorylation and JNK Pathway. Emodin often locates in Membrane, Protoplasm, Mitochondria, Cytoplasmic matrix and soluble. The associated genes with emodin are cytochrome c'', UTS2 gene, TK Gene, Gene Clusters and CFC1 gene. The related lipids are Phosphatidylserines, Promega, Sphingolipids, Membrane Lipids and Palmitates. The related experimental models are Mouse Model and Transgenic Model. |
1742 |
|
Rhein |
Rhein is a lipid of Polyketides (PK) class. Rhein is associated with abnormalities such as Obesity, Non-alcoholic Fatty Liver Disease, Dyslipidemias, Fatty Liver and Degenerative polyarthritis. The involved functions are known as Adipogenesis, Insulin Resistance, luciferase activity, Transcription, Genetic and Inflammation. Rhein often locates in Hepatic, Brown Fat, Muscle, Mouse Liver and Mitochondria. The associated genes with Rhein are QRSL1 gene, Candidate Disease Gene, CFB gene, STAT6 gene and GATA3 gene. The related lipids are Fatty Acids. |
986 |
|
doxorubicin |
Adriamycin is a lipid of Polyketides (PK) class. Adriamycin is associated with abnormalities such as Cardiomyopathies. The involved functions are known as Transcription, Genetic, Process, Drug effect disorder, Diastasis and Oxidation-Reduction. Adriamycin often locates in Muscle, Myocardium and Entire gastrointestinal tract. |
54913 |
|
(-)-Limonene |
(-)-limonene is a lipid of Prenol Lipids (PR) class. (-)-limonene often locates in Kinetochores. |
1786 |
|
(-)-Perillyl alcohol |
(-)-perillyl alcohol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Cell Cycle Progression, Cell Cycle, Cell Proliferation, Apoptosis and Isoprenylation. (-)-perillyl alcohol often locates in Cytoplasm, Membrane and Plasma membrane. The associated genes with (-)-Perillyl alcohol are JUN gene, Candidate Disease Gene, IL24 gene, BCL2L1 gene and CFB gene. The related experimental models are Transgenic Model. |
299 |