Disease MeSH term: Cell Transformation, Neoplastic

Possible associated with:

Structure name description Reference count
phloretin phloretin is a lipid of Polyketides (PK) class. Phloretin is associated with abnormalities such as Atherosclerosis, Diabetes Mellitus, Non-Insulin-Dependent, Alkalemia, Renal tubular disorder and pathologic fistula. The involved functions are known as Anabolism, glycosyltransferase activity, Biosynthetic Pathways, Localized desquamation and Biological Processes. Phloretin often locates in soluble, BL21, Cytoplasmic, Extracellular and Cytoplasm. The associated genes with phloretin are Homologous Gene, CD36 gene, Candidate Disease Gene, SLC33A1 gene and PAK1IP1 gene. The related lipids are Liposomes, Palmitates, Fatty Acids, Sterols and 6-ketocholestanol. The related experimental models are Knock-out. 2367
hesperetin Hesperetin is a lipid of Polyketides (PK) class. Hesperetin is associated with abnormalities such as Corn of toe, Ischemia, Osteoporosis, Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as conjugation, inhibitors, Process, mRNA Expression and Adjudication. Hesperetin often locates in Entire intestinal epithelium, Protoplasm, Membrane, Shoulder and Back. The associated genes with Hesperetin are ABCG2 gene, ABCC2 gene, FATE1 gene, ABCB1 gene and P-glycoprotein 2. 801
AC1MML41 AC1MML41 is a lipid of Polyketides (PK) class. 2
emodin emodin is a lipid of Polyketides (PK) class. Emodin is associated with abnormalities such as Infection, Conjunctivitis, Vernal, Stevens-Johnson Syndrome, Conjunctival scar and Allergic Conjunctivitis. The involved functions are known as signaling cascade, Metabolic Inhibition, Cell Death, Phosphorylation and JNK Pathway. Emodin often locates in Membrane, Protoplasm, Mitochondria, Cytoplasmic matrix and soluble. The associated genes with emodin are cytochrome c'', UTS2 gene, TK Gene, Gene Clusters and CFC1 gene. The related lipids are Phosphatidylserines, Promega, Sphingolipids, Membrane Lipids and Palmitates. The related experimental models are Mouse Model and Transgenic Model. 1742
Rhein Rhein is a lipid of Polyketides (PK) class. Rhein is associated with abnormalities such as Obesity, Non-alcoholic Fatty Liver Disease, Dyslipidemias, Fatty Liver and Degenerative polyarthritis. The involved functions are known as Adipogenesis, Insulin Resistance, luciferase activity, Transcription, Genetic and Inflammation. Rhein often locates in Hepatic, Brown Fat, Muscle, Mouse Liver and Mitochondria. The associated genes with Rhein are QRSL1 gene, Candidate Disease Gene, CFB gene, STAT6 gene and GATA3 gene. The related lipids are Fatty Acids. 986
doxorubicin Adriamycin is a lipid of Polyketides (PK) class. Adriamycin is associated with abnormalities such as Cardiomyopathies. The involved functions are known as Transcription, Genetic, Process, Drug effect disorder, Diastasis and Oxidation-Reduction. Adriamycin often locates in Muscle, Myocardium and Entire gastrointestinal tract. 54913
(-)-Perillyl alcohol (-)-perillyl alcohol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Cell Cycle Progression, Cell Cycle, Cell Proliferation, Apoptosis and Isoprenylation. (-)-perillyl alcohol often locates in Cytoplasm, Membrane and Plasma membrane. The associated genes with (-)-Perillyl alcohol are JUN gene, Candidate Disease Gene, IL24 gene, BCL2L1 gene and CFB gene. The related experimental models are Transgenic Model. 299
(r)-(-)-alpha-phellandrene (r)-(-)-alpha-phellandrene is a lipid of Prenol Lipids (PR) class. 13
Mevalonic acid Mevalonic acid is a lipid of Fatty Acyls (FA) class. 1437
Parthenolide Parthenolide is a lipid of Prenol Lipids (PR) class. Parthenolide is associated with abnormalities such as Migraine Disorders, abnormal fragmented structure, Hyperostosis, Diffuse Idiopathic Skeletal, Consumption-archaic term for TB and Infection. The involved functions are known as Apoptosis, Cell Proliferation, Inflammation, pathologic cytolysis and Membrane Potentials. Parthenolide often locates in Mitochondria, Tissue membrane, Cytoplasmic matrix, Cytoplasm and Body tissue. The associated genes with Parthenolide are IGKJ1 gene, BCL2 gene, DDIT3 gene, Procaspase 7 and GAPDH gene. The related lipids are A(2)C. The related experimental models are Mouse Model, Xenograft Model, Breast Cancer Model and Cancer Model. 925
Gossypol Gossypol is a lipid of Prenol Lipids (PR) class. Gossypol is associated with abnormalities such as Paralytic Ileus, PARKINSON DISEASE, LATE-ONSET, Fibrillation, Hepatic necrosis and Lymphopenia. The involved functions are known as Atrophic, Ulcer, Necrosis, Apoptosis and antagonists. Gossypol often locates in Mucous Membrane, Epithelium, Blood, Microsomes, Liver and Autophagic vacuole. The associated genes with Gossypol are BCL2A1 gene, BCL2 gene, Transgenes, IGH@ gene cluster and Bax protein (53-86). The related lipids are Promega, proteoliposomes, Phosphatidylserines and Liposomes. The related experimental models are Transgenic Model and Xenograft Model. 2557
Thapsigargin Thapsigargin is a lipid of Prenol Lipids (PR) class. Thapsigargin is associated with abnormalities such as Impaired glucose tolerance, Obesity and Blood Pressure Disorders. The involved functions are known as Phosphorylation, establishment and maintenance of localization, Regulation, Metabolic Inhibition and Proteolysis. Thapsigargin often locates in Mouse Skin, Cytoplasm, Skin, Protoplasm and Mitochondria. The associated genes with Thapsigargin are ERBB4 gene, F11 gene, CA1 gene, TRNAP1 gene and HSPA5 gene. The related lipids are taurolithocholic acid 3-sulfate, Liposomes, Fatty Acids and stearylamine. The related experimental models are Mouse Model. 8868
Crocetin Crocetin is a lipid of Prenol Lipids (PR) class. Crocetin is associated with abnormalities such as abnormal fragmented structure, Gout, Infection and athymia. The involved functions are known as Cytokinesis, Anabolism, enzyme mechanism, Pathological accumulation of air in tissues and Hemorrhage. Crocetin often locates in Vacuole, Cytoplasmic matrix, Body tissue, Mitochondria and Blood. The associated genes with Crocetin are cytochrome c'', BCL2 gene and PCNA gene. The related lipids are mycorradicin. 350
forskolin Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides. 24755
Abietic acid Abietic acid is a lipid of Prenol Lipids (PR) class. Abietic acid is associated with abnormalities such as Hand eczema, Dermatitis, Vitelliform dystrophy, Wiskott-Aldrich Syndrome and Dehydration. The involved functions are known as Process, Oxidation, Anabolism, Transmembrane Transport and physiological aspects. Abietic acid often locates in Membrane, Protoplasm, Microsomes and Cellular Membrane. The associated genes with Abietic acid are SLC33A1 gene and ABCG2 gene. The related lipids are Pinene. 280
Phorbol Phorbol is a lipid of Prenol Lipids (PR) class. Phorbol is associated with abnormalities such as furuncle, Infection, endothelial dysfunction, Morphologically altered structure and Acute erythroleukemia. The involved functions are known as Tyrosine Phosphorylation, Metabolic Inhibition, Transcription, Genetic, Protein Biosynthesis and Signal. Phorbol often locates in Tissue membrane, Membrane, Cell surface, soluble and Cytoplasmic Domain. The associated genes with Phorbol are STAT3 gene, JAK2 gene, JUN gene, PROC gene and MAPK8 gene. The related lipids are Lipopolysaccharides, Phosphatidylserines, Liposomes, Fatty Acids and Octanols. 2082
phorbol 13-acetate 12-myristate Phorbol 13-acetate 12-myristate is a lipid of Prenol Lipids (PR) class. The involved functions are known as DNA Fragmentation, Phosphorylation and Irritation. Phorbol 13-acetate 12-myristate often locates in low-density lipoprotein particle. The associated genes with phorbol 13-acetate 12-myristate are FPR1 gene and ABCB1 gene. 40921
Sphinganine Sphinganine is a lipid of Sphingolipids (SP) class. Sphinganine is associated with abnormalities such as Sphingolipidoses, CLEFT LIP, CONGENITAL HEALED, Aortic aneurysm, familial thoracic 4, Morphologically altered structure and Atherosclerosis. The involved functions are known as Transcription, Genetic, Signal, Muscle Contraction, biological adaptation to stress and Gene Expression. Sphinganine often locates in Tissue membrane, Membrane, Protoplasm, Plasma membrane and Cytoplasmic. The associated genes with Sphinganine are SLC33A1 gene, HM13 gene, P4HTM gene, SPHK1 gene and SPHK2 gene. The related lipids are Sphingolipids, Phosphatidylserines, Sterols, Fatty Acids and inositolphosphorylceramide. The related experimental models are Mouse Model and Knock-out. 758
SAFINGOL Safingol is a lipid of Sphingolipids (SP) class. Safingol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Gene Expression, Signal Transduction, Synthesis, Mutation and Adjudication. Safingol often locates in nucleocapsid location. The associated genes with Safingol are Homologous Gene. The related lipids are dihydroceramide and lipid structure. 181
all-trans-retinyl Palmitate All-trans-retinyl palmitate is a lipid of Prenol Lipids (PR) class. All-trans-retinyl palmitate is associated with abnormalities such as Wiskott-Aldrich Syndrome. 1225
13-cis-retinoic acid,Isotretinoin 13-cis-retinoic acid,isotretinoin is a lipid of Prenol Lipids (PR) class. 13-cis-retinoic acid,isotretinoin is associated with abnormalities such as Dermatitis, Phototoxic. The involved functions are known as Regulation, Pigment, chromophore, Light absorption and Pupil constriction. 13-cis-retinoic acid,isotretinoin often locates in Neurosecretory Systems. The associated genes with 13-cis-retinoic acid,Isotretinoin are melanopsin. 4722
Ganglioside GI Ganglioside GI is a lipid of Sphingolipids (SP) class. Ganglioside gi is associated with abnormalities such as HIV Infections, Amyotrophic Lateral Sclerosis, Neuritis, Motor, Motor Neuron Disease and athymia. The involved functions are known as Gene Expression, antigen binding, Protective Agents, Binding (Molecular Function) and response to hormone stimulus. Ganglioside gi often locates in Membrane, Body tissue, Mucous Membrane, integral to membrane and Virion. The associated genes with Ganglioside GI are Fusion Protein, synthetic peptide, CTBS gene, IL2 gene and CD4 gene. The related lipids are Sphingolipids, sialogangliosides, Membrane Lipids, ganglioside, Gx and polysialoganglioside. The related experimental models are Knock-out, Disease model, Experimental Autoimmune Encephalomyelitis, Rodent Model and Transgenic Model. 5081
fumonisin b1 fumonisin b1 is a lipid of Sphingolipids (SP) class. Fumonisin b1 is associated with abnormalities such as Infection, Kidney Diseases, Liver diseases, DERMATITIS HERPETIFORMIS, FAMILIAL and Malnutrition. The involved functions are known as Gene Expression, Anabolism, Signal, Biosynthetic Pathways and Regulation. Fumonisin b1 often locates in Body tissue, Microsomes, microsomal membrane, Protoplasm and Mitochondria. The associated genes with fumonisin b1 are Genome, P4HTM gene, FATE1 gene, BCL2 gene and TMEM132D gene. The related lipids are dihydroceramide, ceramide 1-phosphate, Sphingolipids, Fatty Acids and Palmitates. 902
N-acetylsphingosine N-acetylsphingosine is a lipid of Sphingolipids (SP) class. N-acetylsphingosine is associated with abnormalities such as Morphologically altered structure, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and Gigantism. The involved functions are known as inhibitors, anti-apoptosis, Apoptosis, Dephosphorylation and immunoreactivity. N-acetylsphingosine often locates in Plasma membrane, Mitochondria, Pore, Membrane and Cytoplasmic matrix. The associated genes with N-acetylsphingosine are EGR3 gene, CFB gene, FATE1 gene, P4HTM gene and PFDN4 gene. The related lipids are Sphingolipids, Cardiolipins, Glycerophospholipids, dihydroceramide and Phosphatidic Acid. 633
cholesterol cholesterol is a lipid of Sterol Lipids (ST) class. Cholesterol is associated with abnormalities such as Trypanosomiasis, Chagas Disease, Cleft Palate, Chondrodysplasia punctata 2, X-linked dominant and Child syndrome. The involved functions are known as Blood Circulation, Sterol Biosynthesis Pathway, Receptor Mediated Endocytosis, Methylation and Signal. Cholesterol often locates in Animal tissue, Blood, Membrane, Plasma membrane and peroxisome. The associated genes with cholesterol are MBD2 gene, SIM, SLC33A1 gene, Genome and NSDHL gene. The related lipids are Sterols, zymosterol, fecosterol, Total cholesterol and 7-dehydrocholesterol. The related experimental models are Mouse Model, Knock-out, Genetically Engineered Mouse and Disease model. 98461
Beta-estradiol Beta-estradiol is a lipid of Sterol Lipids (ST) class. Beta-estradiol is associated with abnormalities such as endothelial dysfunction, PARKINSON DISEASE, LATE-ONSET, Pregnancy Related and Neuromuscular Diseases. The involved functions are known as physiological aspects, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Contraction (finding), Muscle Contraction and Metabolic Inhibition. Beta-estradiol often locates in Endothelium, Arterial system, Blood Vessel Tissue, Microsomes, Liver and Neurites. The associated genes with Beta-estradiol are FGF4 gene. The related lipids are estradiol-3-glucuronide. 74916
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