Disease MeSH term: Chemical and Drug Induced Liver Injury

Possible associated with:

Structure name description Reference count
Gossypol Gossypol is a lipid of Prenol Lipids (PR) class. Gossypol is associated with abnormalities such as Paralytic Ileus, PARKINSON DISEASE, LATE-ONSET, Fibrillation, Hepatic necrosis and Lymphopenia. The involved functions are known as Atrophic, Ulcer, Necrosis, Apoptosis and antagonists. Gossypol often locates in Mucous Membrane, Epithelium, Blood, Microsomes, Liver and Autophagic vacuole. The associated genes with Gossypol are BCL2A1 gene, BCL2 gene, Transgenes, IGH@ gene cluster and Bax protein (53-86). The related lipids are Promega, proteoliposomes, Phosphatidylserines and Liposomes. The related experimental models are Transgenic Model and Xenograft Model. 2557
ZEARALENONE ZEARALENONE is a lipid of Polyketides (PK) class. Zearalenone is associated with abnormalities such as HYPOTRICHOSIS, LOCALIZED, AUTOSOMAL RECESSIVE, 2, Estrogen excess, Food-Drug Interactions, Osteomalacia and Osteoporosis. The involved functions are known as mRNA Expression, Metabolic Inhibition, Phosphorylation, Agent and Transcriptional Activation. Zearalenone often locates in Gastrointestinal tract structure, soluble, viral nucleocapsid location, Spindle and Hepatic. The associated genes with ZEARALENONE are Candidate Disease Gene, Genome, Genes, Reporter, P4HTM gene and Open Reading Frames. The related lipids are Lipopolysaccharides, Steroids, Fatty Acids and Promega. The related experimental models are Transgenic Model. 2573
2,3-butanedione 2,3-butanedione is a lipid of Fatty Acyls (FA) class. The involved functions are known as Physiologic Organization, Biochemical Pathway, physiological aspects, establishment and maintenance of localization and Phosphorylation. 2,3-butanedione often locates in Membrane, Microfilaments, Microtubules, Cell body of neuron and filamentous actin location. The associated genes with 2,3-butanedione are SLC33A1 gene and WASF1 gene. 2715
Oxalacetic acid Oxalacetic acid is a lipid of Fatty Acyls (FA) class. 3226
apigenin apigenin is a lipid of Polyketides (PK) class. Apigenin is associated with abnormalities such as Morphologically altered structure, Chimera disorder, Hypertensive disease, infection induced and Infection. The involved functions are known as inhibitors, Gene Expression, Process, Metabolic Inhibition and Cell Death. Apigenin often locates in Vacuole, Cytoplasmic matrix, Cytoplasm, Tissue membrane and Membrane. The associated genes with apigenin are MSMP gene, BCL2 gene, PTGS2 gene, Chromatin and SLC33A1 gene. The related lipids are Lipopolysaccharides, Steroids, 1-Butanol, agosterol A and Butyrates. The related experimental models are Mouse Model, Tissue Model, Knock-out, Xenograft Model and Disease model. 4250
quercetin quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model. 5377
4-hydroxynonenal 4-hydroxynonenal is a lipid of Fatty Acyls (FA) class. 4-hydroxynonenal is associated with abnormalities such as Chronic disease, Obesity, Diabetes, Acquired Immunodeficiency Syndrome and Lung diseases. The involved functions are known as protein expression, Glycolysis, mRNA Expression, Regulation and Mitochondrion in division. 4-hydroxynonenal often locates in Muscle, Mitochondria, Adipose tissue, Head and Mouse Muscle. The associated genes with 4-hydroxynonenal are STAT3 gene, SIRT1 gene, PGC gene, IL6 gene and cytochrome c''. The related lipids are Lipopolysaccharides, Lipid Peroxides, Promega, Membrane Lipids and oxidized lipid. The related experimental models are Mouse Model, Knock-out, Transgenic Model, Disease model and Rodent Model. 5685
AFBI AFBI is a lipid of Polyketides (PK) class. Afbi is associated with abnormalities such as Pyotraumatic dermatitis, Infection, Hepatitis, Liver diseases and Hepatitis B. The involved functions are known as Immune response, Mutation, Anabolism, Metabolic Inhibition and Increased Sensitivy. Afbi often locates in Body tissue, Hepatic, Cytoplasm, Blood and Micronucleus. The associated genes with AFBI are TP53 gene, Genome, Transgenes, FATE1 gene and MANEA gene. The related lipids are Lipopolysaccharides, Lipid Peroxides, 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole and Liposomes. 5774
18194-24-6 18194-24-6 is a lipid of Glycerophospholipids (GP) class. 18194-24-6 is associated with abnormalities such as Cerebrovascular accident, Renal tubular disorder, Atherosclerosis, Hyperlipoproteinemia Type III and Lipid Metabolism Disorders. The involved functions are known as Process, protein folding, Catalyst, Biochemical Pathway and Fold in Medical Device Material. 18194-24-6 often locates in Tissue membrane, Membrane, periplasm, vesicle membrane and outer membrane. The associated genes with 18194-24-6 are Integral Membrane Proteins, Protein Structure, RTN4 gene, RTN4R gene and Protein, Organized by Structure. The related lipids are Micelles, dimyristoylphosphatidylglycerol, 1,2-dihexadecyl-sn-glycero-3-phosphocholine, Unilamellar Vesicles and cholesteryl oleate. The related experimental models are Mouse Model, Arthritis, Adjuvant-Induced, Disease model and Xenograft Model. 6350
PGD2 Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model. 6464
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