2,2-DIMETHYLBUTYRIC ACID

2,2-DIMETHYLBUTYRIC ACID is a lipid of Fatty Acyls (FA) class. The involved functions are known as Fermentation, Process, Intestinal Absorption, Energy Metabolism and Proteolysis. 2,2-dimethylbutyric acid often locates in host and Hepatic. The related lipids are Propionate, Butyrates, n-Butyrate, Valerates and blood lipid.

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Introduction

To understand associated biological information of 2,2-DIMETHYLBUTYRIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2,2-DIMETHYLBUTYRIC ACID?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2,2-DIMETHYLBUTYRIC ACID

MeSH term MeSH ID Detail
Gastritis D005756 27 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Sickle Cell Trait D012805 4 associated lipids
beta-Thalassemia D017086 5 associated lipids
Total 4

PubChem Associated disorders and diseases

What pathways are associated with 2,2-DIMETHYLBUTYRIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2,2-DIMETHYLBUTYRIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2,2-DIMETHYLBUTYRIC ACID?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2,2-DIMETHYLBUTYRIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2,2-DIMETHYLBUTYRIC ACID?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 2,2-DIMETHYLBUTYRIC ACID?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2,2-DIMETHYLBUTYRIC ACID

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Authors Title Published Journal PubMed Link
Perrine SP et al. Evaluation of safety and pharmacokinetics of sodium 2,2 dimethylbutyrate, a novel short chain fatty acid derivative, in a phase 1, double-blind, placebo-controlled, single-dose, and repeat-dose studies in healthy volunteers. 2011 J Clin Pharmacol pmid:21422239
Terse PS et al. Short-term toxicity study of ST-20 (NSC-741804) by oral gavage in Sprague-Dawley rats. 2011 Toxicol Pathol pmid:21558467
Wang H et al. In-situ XAFS studies of Mn12 molecular-cluster batteries: super-reduced Mn12 clusters in solid-state electrochemistry. 2011 Chem Asian J pmid:21265025
Perrine SP et al. Fetal globin gene inducers: novel agents and new potential. 2010 Ann. N. Y. Acad. Sci. pmid:20712788
Galanello R and Origa R Beta-thalassemia. 2010 Orphanet J Rare Dis pmid:20492708
Barrios-González J and Miranda RU Biotechnological production and applications of statins. 2010 Appl. Microbiol. Biotechnol. pmid:19820926
Parise RA et al. Liquid chromatography-mass spectrometric assay for quantitation of the short-chain fatty acid, 2,2-dimethylbutyrate (NSC 741804), in rat plasma. 2008 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:18155649
Martin FP et al. Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model. 2008 Mol. Syst. Biol. pmid:18197175
Martin FP et al. Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model. 2008 Mol. Syst. Biol. pmid:18628745
Martin FP et al. A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model. 2007 Mol. Syst. Biol. pmid:17515922