2-ETHYLHEXANOIC ACID is a lipid of Fatty Acyls (FA) class. The involved functions are known as Steroid biosynthesis, cholesterol metabolic process, cholesterol transport, Cell Proliferation and progesterone biosynthetic process. 2-ethylhexanoic acid often locates in Organelles, Tissue membrane, Mitochondria, Mitochondrial Membranes and Cytoplasm. The associated genes with 2-ETHYLHEXANOIC ACID are steroidogenic acute regulatory protein and SLC27A1 gene. The related lipids are 2-ethylhexanoic acid, Steroids, Hexanols and (22R)-22-hydroxycholesterol.
To understand associated biological information of 2-ETHYLHEXANOIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with 2-ETHYLHEXANOIC ACID
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Acne Vulgaris | D000152 | 35 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Hydrocephalus | D006849 | 6 associated lipids |
| Spinal Dysraphism | D016135 | 1 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
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| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lundgren B et al. | Induction of cytosolic and microsomal epoxide hydrolases in mouse liver by peroxisome proliferators, with special emphasis on structural analogues of 2-ethylhexanoic acid. | 1988 | Chem. Biol. Interact. | pmid:3214886 |
| Norplant update. | 1988 | Netw Res Triangle Park N C | pmid:12280954 | |
| Lundgren B et al. | Characterization of the induction of cytosolic and microsomal epoxide hydrolases by 2-ethylhexanoic acid in mouse liver. | 1987 Jan-Feb | Drug Metab. Dispos. | pmid:2881746 |
| Ritter EJ et al. | Teratogenicity of di(2-ethylhexyl) phthalate, 2-ethylhexanol, 2-ethylhexanoic acid, and valproic acid, and potentiation by caffeine. | 1987 | Teratology | pmid:3105103 |
| Lundgren B et al. | Examination of the structural requirements for proliferation of peroxisomes and mitochondria in mouse liver by hypolipidemic agents, with special emphasis on structural analogues of 2-ethylhexanoic acid. | 1987 | Eur. J. Biochem. | pmid:3028804 |
| De Jongh KS et al. | Kinetic mechanism of sheep liver NADPH-dependent aldehyde reductase. | 1987 | Biochem. J. | pmid:3593233 |
| Casperson G et al. | [Effect of 2-ethyl-2-ene-1-al and analogous compounds on the growth and ultrastructure of fungi]. | 1986 | J. Basic Microbiol. | pmid:3097298 |
| Burton GJ et al. | The use of lead methacrylate 2-ethylhexanoate to create a radio-opaque resin suitable for microvascular corrosion casting. | 1986 | J Microsc | pmid:3783666 |
| Dickinson RG et al. | "Radiochemically pure [1-14C]valproic acid"--a mixture of labeled structural isomers. | 1986 | Ther Drug Monit | pmid:3103265 |
| Misra DN | Adsorption of zirconyl salts and their acids on hydroxyapatite: use of the salts as coupling agents to dental polymer composites. | 1985 | J. Dent. Res. | pmid:3001161 |