| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Cell Transformation, Neoplastic | D002471 | 126 associated lipids |
| Alzheimer Disease | D000544 | 76 associated lipids |
| Neuroblastoma | D009447 | 66 associated lipids |
| Leukemia-Lymphoma, Adult T-Cell | D015459 | 25 associated lipids |
| Parkinsonian Disorders | D020734 | 20 associated lipids |
Epothilone D
Epothilone d is a lipid of Polyketides (PK) class. Epothilone d is associated with abnormalities such as Tauopathies, Neutropenia, Neuropathy and Hematological Disease. The involved functions are known as Mutation, Apoptosis, Mitotic arrest, Cell Growth and Anabolism. Epothilone d often locates in Cytoskeleton, Axon, Cell Wall, Chromosomes and Spindle. The associated genes with epothilone D are SLC33A1 gene, Chromatin, GTF2I gene and HEXA gene.
Cross Reference
Introduction
To understand associated biological information of Epothilone D, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Epothilone D?
Epothilone D is suspected in Tauopathies, Neutropenia, Neuropathy, Hematological Disease and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Epothilone D
PubChem Associated disorders and diseases
What pathways are associated with Epothilone D
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Epothilone D?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Epothilone D?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Epothilone D?
There are no associated biomedical information in the current reference collection.
What genes are associated with Epothilone D?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Epothilone D?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Epothilone D
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Verrills NM et al. | Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia. | 2006 | J. Natl. Cancer Inst. | pmid:17018783 |
| Wang Z et al. | Determination of desoxyepothilone B in nude mice plasma by liquid-liquid extraction and reversed-phase high-performance liquid chromatography. | 2006 | J Pharm Biomed Anal | pmid:16616824 |
| Kuppens IE | Current state of the art of new tubulin inhibitors in the clinic. | 2006 | Curr Clin Pharmacol | pmid:18666378 |
| Frykman SA et al. | Assessment of fed-batch, semicontinuous, and continuous epothilone D production processes. | 2005 Jul-Aug | Biotechnol. Prog. | pmid:16080689 |
| Gaich T and Mulzer J | Synthesis of epothilones via a silicon-tethered RCM reaction. | 2005 | Org. Lett. | pmid:15787494 |
| Wang H et al. | Preclinical pharmacology of epothilone D, a novel tubulin-stabilizing antitumor agent. | 2005 | Cancer Chemother. Pharmacol. | pmid:15868148 |
| Broadrup RL et al. | Total synthesis of 12,13-desoxyepothilone B (Epothilone D). | 2005 | Bioorg. Chem. | pmid:15788167 |
| Hause G et al. | Epothilone D affects cell cycle and microtubular pattern in plant cells. | 2005 | J. Exp. Bot. | pmid:15967777 |
| Jumaa M et al. | Kinetics and mechanism of degradation of epothilone-D: an experimental anticancer agent. | 2004 | J Pharm Sci | pmid:15459947 |
| Bergstralh DT et al. | A comparison of signaling activities induced by Taxol and desoxyepothilone B. | 2004 | J Chemother | pmid:15700849 |