HEMATOXYLIN is a lipid of Polyketides (PK) class. Hematoxylin is associated with abnormalities such as Eosinophilia, Duodenal Adenoma, Senile Plaques, Morphologically altered structure and Cervical abscess. The involved functions are known as Uptake, Apoptosis, Amplification, Necrosis and Karyopyknosis. Hematoxylin often locates in Body tissue, Extracellular, Compact bone, Skin and Basement membrane. The associated genes with HEMATOXYLIN are GAPDH gene, Genome, Elastin, MERTK wt Allele and P4HTM gene.
To understand associated biological information of HEMATOXYLIN, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
HEMATOXYLIN is suspected in Senile Plaques, Eosinophilia, Duodenal Adenoma, Morphologically altered structure, Cervical abscess and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with HEMATOXYLIN
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Szyszko EA et al. | Salivary glands of primary Sjögren's syndrome patients express factors vital for plasma cell survival. | 2011 | Arthritis Res. Ther. | pmid:21214903 |
Hui W et al. | A model of inflammatory arthritis highlights a role for oncostatin M in pro-inflammatory cytokine-induced bone destruction via RANK/RANKL. | 2005 | Arthritis Res. Ther. | pmid:15642143 |
Sumariwalla PF et al. | The angiogenesis inhibitor protease-activated kringles 1-5 reduces the severity of murine collagen-induced arthritis. | 2003 | Arthritis Res. Ther. | pmid:12716451 |
Kelchtermans H et al. | Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-gamma. | 2005 | Arthritis Res. Ther. | pmid:15743488 |
Frey O et al. | The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4+CD25+ T cells. | 2005 | Arthritis Res. Ther. | pmid:15743476 |
Pessler F et al. | Identification of novel monosodium urate crystal regulated mRNAs by transcript profiling of dissected murine air pouch membranes. | 2008 | Arthritis Res. Ther. | pmid:18522745 |
Khan WS et al. | Hypoxic conditions increase hypoxia-inducible transcription factor 2alpha and enhance chondrogenesis in stem cells from the infrapatellar fat pad of osteoarthritis patients. | 2007 | Arthritis Res. Ther. | pmid:17537234 |
Gilbert HT et al. | The involvement of interleukin-1 and interleukin-4 in the response of human annulus fibrosus cells to cyclic tensile strain: an altered mechanotransduction pathway with degeneration. | 2011 | Arthritis Res. Ther. | pmid:21276216 |
Jin T et al. | Urokinase, a constitutive component of the inflamed synovial fluid, induces arthritis. | 2003 | Arthritis Res. Ther. | pmid:12716448 |
Magnusson SE et al. | High synovial expression of the inhibitory FcgammaRIIb in rheumatoid arthritis. | 2007 | Arthritis Res. Ther. | pmid:17521421 |
Fickert S et al. | Identification of subpopulations with characteristics of mesenchymal progenitor cells from human osteoarthritic cartilage using triple staining for cell surface markers. | 2004 | Arthritis Res. Ther. | pmid:15380042 |
Inman RD and Chiu B | Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis. | 2009 | Arthritis Res. Ther. | pmid:19203382 |
Berggreen E et al. | Impaired vascular responses to parasympathetic nerve stimulation and muscarinic receptor activation in the submandibular gland in nonobese diabetic mice. | 2009 | Arthritis Res. Ther. | pmid:19200376 |
Findlay D et al. | Circulating RANKL is inversely related to RANKL mRNA levels in bone in osteoarthritic males. | 2008 | Arthritis Res. Ther. | pmid:18182105 |
Moran EM et al. | Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-alpha, Oncostatin M and response to biologic therapies. | 2009 | Arthritis Res. Ther. | pmid:19627579 |
Iwanami K et al. | Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis. | 2008 | Arthritis Res. Ther. | pmid:18992137 |
Goedkoop AY et al. | Deactivation of endothelium and reduction in angiogenesis in psoriatic skin and synovium by low dose infliximab therapy in combination with stable methotrexate therapy: a prospective single-centre study. | 2004 | Arthritis Res. Ther. | pmid:15225368 |
Le Maitre CL et al. | Expression of cartilage-derived morphogenetic protein in human intervertebral discs and its effect on matrix synthesis in degenerate human nucleus pulposus cells. | 2009 | Arthritis Res. Ther. | pmid:19754961 |
Delaleu N et al. | Biomarker profiles in serum and saliva of experimental Sjögren's syndrome: associations with specific autoimmune manifestations. | 2008 | Arthritis Res. Ther. | pmid:18289371 |
Tomita T et al. | THR0921, a novel peroxisome proliferator-activated receptor gamma agonist, reduces the severity of collagen-induced arthritis. | 2006 | Arthritis Res. Ther. | pmid:16356194 |
Trachsel E et al. | Antibody-mediated delivery of IL-10 inhibits the progression of established collagen-induced arthritis. | 2007 | Arthritis Res. Ther. | pmid:17261171 |
Park YS et al. | Intra-articular injection of a nutritive mixture solution protects articular cartilage from osteoarthritic progression induced by anterior cruciate ligament transection in mature rabbits: a randomized controlled trial. | 2007 | Arthritis Res. Ther. | pmid:17257416 |
Richardson SM et al. | Increased expression of matrix metalloproteinase-10, nerve growth factor and substance P in the painful degenerate intervertebral disc. | 2009 | Arthritis Res. Ther. | pmid:19695094 |
Dharmapatni AA et al. | TWEAK and Fn14 expression in the pathogenesis of joint inflammation and bone erosion in rheumatoid arthritis. | 2011 | Arthritis Res. Ther. | pmid:21435232 |
Reefman E et al. | Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus? | 2006 | Arthritis Res. Ther. | pmid:17014704 |
Richardson D et al. | Characterisation of the cannabinoid receptor system in synovial tissue and fluid in patients with osteoarthritis and rheumatoid arthritis. | 2008 | Arthritis Res. Ther. | pmid:18416822 |
Gompels LL et al. | Human epidermal growth factor receptor bispecific ligand trap RB200: abrogation of collagen-induced arthritis in combination with tumour necrosis factor blockade. | 2011 | Arthritis Res. Ther. | pmid:21982514 |
Mason LJ et al. | Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity. | 2005 | Arthritis Res. Ther. | pmid:16207338 |
McCann FE et al. | Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis. | 2010 | Arthritis Res. Ther. | pmid:20525198 |
Ochaion A et al. | Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A3 adenosine receptor expression. | 2006 | Arthritis Res. Ther. | pmid:17101059 |
Bainbridge J et al. | Methionine aminopeptidase-2 blockade reduces chronic collagen-induced arthritis: potential role for angiogenesis inhibition. | 2007 | Arthritis Res. Ther. | pmid:18072970 |
Van Praet JT et al. | Histopathological cutaneous alterations in systemic sclerosis: a clinicopathological study. | 2011 | Arthritis Res. Ther. | pmid:21356083 |
Kop EN et al. | CD97 neutralisation increases resistance to collagen-induced arthritis in mice. | 2006 | Arthritis Res. Ther. | pmid:17007638 |
Inglis JJ et al. | Collagen-induced arthritis in C57BL/6 mice is associated with a robust and sustained T-cell response to type II collagen. | 2007 | Arthritis Res. Ther. | pmid:17967186 |
Hjelmervik TO et al. | The influence of the NOD Nss1/Idd5 loci on sialadenitis and gene expression in salivary glands of congenic mice. | 2007 | Arthritis Res. Ther. | pmid:17900348 |
van de Breevaart Bravenboer J et al. | Improved cartilage integration and interfacial strength after enzymatic treatment in a cartilage transplantation model. | 2004 | Arthritis Res. Ther. | pmid:15380046 |
Butoescu N et al. | Magnetically retainable microparticles for drug delivery to the joint: efficacy studies in an antigen-induced arthritis model in mice. | 2009 | Arthritis Res. Ther. | pmid:19454011 |
Brun P et al. | Characteristics of repair tissue in second-look and third-look biopsies from patients treated with engineered cartilage: relationship to symptomatology and time after implantation. | 2008 | Arthritis Res. Ther. | pmid:19014452 |
Scirè CA et al. | Immunohistological assessment of the synovial tissue in small joints in rheumatoid arthritis: validation of a minimally invasive ultrasound-guided synovial biopsy procedure. | 2007 | Arthritis Res. Ther. | pmid:17903238 |
De Klerck B et al. | Enhanced osteoclast development in collagen-induced arthritis in interferon-gamma receptor knock-out mice as related to increased splenic CD11b+ myelopoiesis. | 2004 | Arthritis Res. Ther. | pmid:15142268 |
Sundberg E et al. | Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients--a prospective clinical study. | 2008 | Arthritis Res. Ther. | pmid:18346273 |
Zhao X et al. | Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis. | 2008 | Arthritis Res. Ther. | pmid:18710572 |
Tolofari SK et al. | Expression of semaphorin 3A and its receptors in the human intervertebral disc: potential role in regulating neural ingrowth in the degenerate intervertebral disc. | 2010 | Arthritis Res. Ther. | pmid:20051117 |
Schmutz C et al. | Chemokine receptors in the rheumatoid synovium: upregulation of CXCR5. | 2005 | Arthritis Res. Ther. | pmid:15743468 |
Giatromanolaki A et al. | Upregulated hypoxia inducible factor-1alpha and -2alpha pathway in rheumatoid arthritis and osteoarthritis. | 2003 | Arthritis Res. Ther. | pmid:12823854 |
Sharma A et al. | Glycosaminoglycan profiles of repair tissue formed following autologous chondrocyte implantation differ from control cartilage. | 2007 | Arthritis Res. Ther. | pmid:17697352 |
Young CL et al. | Immunohistologic characterization of synovial membrane lymphocytes in rheumatoid arthritis. | 1984 | Arthritis Rheum. | pmid:6197977 |
Wang Y et al. | Polymerized human placenta hemoglobin (PolyPHb) attenuates myocardial infarction injury in rats. | 2012 | Artif Cells Blood Substit Immobil Biotechnol | pmid:21623696 |
He H et al. | Laser-capture microdissection and protein extraction for protein fingerprint of OSCC and OLK. | 2009 | Artif Cells Blood Substit Immobil Biotechnol | pmid:19735007 |
Gangopadhyay AN et al. | Histology of the terminal end of the distal rectal pouch and fistula region in anorectal malformations. | 2008 | Asian J Surg | pmid:19010766 |