chrysin

chrysin is a lipid of Polyketides (PK) class. Chrysin is associated with abnormalities such as Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and Colitis. The involved functions are known as Hypoxia, enzyme activity, Oxidation, inhibitors and Cell Survival. Chrysin often locates in Protoplasm, Plasma membrane, Back, Extracellular and Mitochondria. The associated genes with chrysin are CFB gene, P4HTM gene, UGT1A9 gene, CYP1A1 gene and UGT1A1 gene. The related lipids are Promega, estradiol-3-glucuronide, Steroids and Lipopolysaccharides. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of chrysin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with chrysin?

chrysin is suspected in Colitis, Toxic nephropathy, Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with chrysin

MeSH term MeSH ID Detail
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Inflammation D007249 119 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Precancerous Conditions D011230 48 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with chrysin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with chrysin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with chrysin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with chrysin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with chrysin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with chrysin?

Mouse Model

Mouse Model are used in the study 'Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-κB signaling pathway.' (Dou W et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with chrysin

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Authors Title Published Journal PubMed Link
Salimi A et al. Chrysin as an Anti-Cancer Agent Exerts Selective Toxicity by Directly Inhibiting Mitochondrial Complex II and V in CLL B-lymphocytes. 2017 Cancer Invest. pmid:28301251
Ryu S et al. Chrysin induces death of prostate cancer cells by inducing ROS and ER stress. 2017 J. Cell. Physiol. pmid:28213961
Mohammadi Z et al. The Effect of Chrysin Loaded PLGA-PEG on Metalloproteinase Gene Expression in Mouse 4T1 Tumor Model. 2017 Drug Res (Stuttg) pmid:28166590
Mani R et al. Neuroprotective effect of chrysin on hyperammonemia mediated neuroinflammatory responses and altered expression of astrocytic protein in the hippocampus. 2017 Biomed. Pharmacother. pmid:28157652
Choi JK et al. Chrysin attenuates atopic dermatitis by suppressing inflammation of keratinocytes. 2017 Food Chem. Toxicol. pmid:29050978
Lee BK et al. Chrysin Attenuates VCAM-1 Expression and Monocyte Adhesion in Lipopolysaccharide-Stimulated Brain Endothelial Cells by Preventing NF-κB Signaling. 2017 Int J Mol Sci pmid:28671640
Mohammadian F et al. Chrysin Alters microRNAs Expression Levels in Gastric Cancer Cells: Possible Molecular Mechanism. 2017 Drug Res (Stuttg) pmid:28628924
Lin S et al. Synthesis, characterization and xanthine oxidase inhibition of Cu(II)-chrysin complex. 2017 Spectrochim Acta A Mol Biomol Spectrosc pmid:28167361
Xie Z et al. Sensitive, simultaneous determination of chrysin and baicalein based on TaO-chitosan composite modified carbon paste electrode. 2017 Talanta pmid:28153298
Dong D et al. Sodium Oleate-Based Nanoemulsion Enhances Oral Absorption of Chrysin through Inhibition of UGT-Mediated Metabolism. 2017 Mol. Pharm. pmid:27983856