chrysin

chrysin is a lipid of Polyketides (PK) class. Chrysin is associated with abnormalities such as Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and Colitis. The involved functions are known as Hypoxia, enzyme activity, Oxidation, inhibitors and Cell Survival. Chrysin often locates in Protoplasm, Plasma membrane, Back, Extracellular and Mitochondria. The associated genes with chrysin are CFB gene, P4HTM gene, UGT1A9 gene, CYP1A1 gene and UGT1A1 gene. The related lipids are Promega, estradiol-3-glucuronide, Steroids and Lipopolysaccharides. The related experimental models are Mouse Model.

Cross Reference

Introduction

To understand associated biological information of chrysin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with chrysin?

chrysin is suspected in Colitis, Toxic nephropathy, Unconjugated hyperbilirubinemia, Metabolic Diseases, Hypogonadism, Renal tubular disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with chrysin

MeSH term MeSH ID Detail
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Kidney Neoplasms D007680 29 associated lipids
Inflammation D007249 119 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Precancerous Conditions D011230 48 associated lipids
Per page 10 20 50 | Total 28

PubChem Associated disorders and diseases

What pathways are associated with chrysin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with chrysin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with chrysin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with chrysin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with chrysin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with chrysin?

Mouse Model

Mouse Model are used in the study 'Chrysin ameliorates chemically induced colitis in the mouse through modulation of a PXR/NF-κB signaling pathway.' (Dou W et al., 2013).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with chrysin

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Authors Title Published Journal PubMed Link
Singh J et al. Baicalin and chrysin mixture imparts cyto-protection against methylglyoxal induced cytotoxicity and diabetic tubular injury by modulating RAGE, oxidative stress and inflammation. 2017 Environ. Toxicol. Pharmacol. pmid:28135651
Kang MK et al. Chrysin ameliorates podocyte injury and slit diaphragm protein loss via inhibition of the PERK-eIF2α-ATF-CHOP pathway in diabetic mice. 2017 Acta Pharmacol. Sin. pmid:28502979
Dong D et al. Sodium Oleate-Based Nanoemulsion Enhances Oral Absorption of Chrysin through Inhibition of UGT-Mediated Metabolism. 2017 Mol. Pharm. pmid:27983856
Lim HK et al. Chrysin Increases the Therapeutic Efficacy of Docetaxel and Mitigates Docetaxel-Induced Edema. 2017 Integr Cancer Ther pmid:27151585
Eatemadi A et al. Synthesis and Characterization of Chrysin-loaded PCL-PEG-PCL nanoparticle and its effect on breast cancer cell line. 2016 Biomed. Pharmacother. pmid:27847208
Filho CB et al. Chrysin promotes attenuation of depressive-like behavior and hippocampal dysfunction resulting from olfactory bulbectomy in mice. 2016 Chem. Biol. Interact. pmid:27818124
Samarghandian S et al. Chrysin treatment improves diabetes and its complications in liver, brain, and pancreas in streptozotocin-induced diabetic rats. 2016 Can. J. Physiol. Pharmacol. pmid:26863330
Yao J et al. Chrysin alleviates allergic inflammation and airway remodeling in a murine model of chronic asthma. 2016 Int. Immunopharmacol. pmid:26780233
Mohammadian F et al. Down regulation of miR-18a, miR-21 and miR-221 genes in gastric cancer cell line by chrysin-loaded PLGA-PEG nanoparticles. 2016 Artif Cells Nanomed Biotechnol pmid:26772615
Hsu YM et al. 3-Methyl-4,5-dihydro-oxepine, polyoxygenated seco-cyclohexenes and cyclohexenes from Uvaria flexuosa and their anti-inflammatory activity. 2016 Phytochemistry pmid:26732672