| MeSH term | MeSH ID | Detail |
|---|---|---|
| Inflammatory Bowel Diseases | D015212 | 9 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Metabolism, Inborn Errors | D008661 | 46 associated lipids |
| Amino Acid Metabolism, Inborn Errors | D000592 | 16 associated lipids |
| Olfaction Disorders | D000857 | 17 associated lipids |
| Maple Syrup Urine Disease | D008375 | 5 associated lipids |
| Acidosis, Renal Tubular | D000141 | 4 associated lipids |
| Fanconi Syndrome | D005198 | 4 associated lipids |
| Lipid Metabolism, Inborn Errors | D008052 | 26 associated lipids |
| Dwarfism | D004392 | 1 associated lipids |
ISOVALERIC ACID
ISOVALERIC ACID is a lipid of Fatty Acyls (FA) class. Isovaleric acid is associated with abnormalities such as Infection, Lymphocele, Cyst, Abscess and Subgingival plaque. The involved functions are known as Biochemical Reaction, 5-(carboxyamino)imidazole ribonucleotide mutase activity, nitrate reductase activity, urease activity and colony morphology. Isovaleric acid often locates in Skeleton, Abdomen, Chromosomes, Tissue membrane and Microsomes. The associated genes with ISOVALERIC ACID are trypticase, Operon, KCNT1 gene, Genome and Reverse primer. The related lipids are Fatty Acids, Propionate, Fatty Acids, Unsaturated, Steroids and Promega. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of ISOVALERIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with ISOVALERIC ACID?
ISOVALERIC ACID is suspected in Exanthema, Isovaleryl-CoA dehydrogenase deficiency, Subgingival plaque, Dehydration, MAJOR DEPRESSIVE DISORDER 1, MAJOR DEPRESSIVE DISORDER 2 and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with ISOVALERIC ACID
PubChem Associated disorders and diseases
What pathways are associated with ISOVALERIC ACID
Lipid pathways are not clear in current pathway databases. We organized associated pathways with ISOVALERIC ACID through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with ISOVALERIC ACID?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with ISOVALERIC ACID?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with ISOVALERIC ACID?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with ISOVALERIC ACID?
Related references are published most in these journals:
- Appl. Environ. Microbiol. (4)
- Int. J. Syst. Evol. Microbiol. (3)
- Microbiology (Reading, Engl.) (2)
- Others (7)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with ISOVALERIC ACID?
Knock-out
Knock-out are used in the study '3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation.' (Bode HB et al., 2006) and Knock-out are used in the study 'Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized.' (Ruan Y et al., 2001).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with ISOVALERIC ACID
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Parma V et al. | Subliminally perceived odours modulate female intrasexual competition: an eye movement study. | 2012 | PLoS ONE | pmid:22383968 |
| Dadamio J et al. | Clinical utility of a novel colorimetric chair side test for oral malodour. | 2012 | J. Clin. Periodontol. | pmid:22612797 |
| Mukabana WR et al. | A novel synthetic odorant blend for trapping of malaria and other African mosquito species. | 2012 | J. Chem. Ecol. | pmid:22426893 |
| Sharp MD et al. | Rapid discrimination and characterization of vanilla bean extracts by attenuated total reflection infrared spectroscopy and selected ion flow tube mass spectrometry. | 2012 | J. Food Sci. | pmid:22384952 |
| Seo YS et al. | Removal of off-flavors from sea tangle (Laminaria japonica) extract by fermentation with Aspergillus oryzae. | 2012 | Bioresour. Technol. | pmid:22840201 |
| Liu XG et al. | In vivo antidepressant activity of sesquiterpenes from the roots of Valeriana fauriei Briq. | 2012 | Fitoterapia | pmid:22285939 |
| Welke JE et al. | Characterization of the volatile profile of Brazilian Merlot wines through comprehensive two dimensional gas chromatography time-of-flight mass spectrometric detection. | 2012 | J Chromatogr A | pmid:22277184 |
| Grünert SC et al. | Clinical and neurocognitive outcome in symptomatic isovaleric acidemia. | 2012 | Orphanet J Rare Dis | pmid:22277694 |
| Davis CK et al. | Isolation and survey of novel fluoroacetate-degrading bacteria belonging to the phylum Synergistetes. | 2012 | FEMS Microbiol. Ecol. | pmid:22372434 |
| Chang P et al. | The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium. | 2012 | Dis Model Mech | pmid:21876211 |