ISOVALERIC ACID

ISOVALERIC ACID is a lipid of Fatty Acyls (FA) class. Isovaleric acid is associated with abnormalities such as Infection, Lymphocele, Cyst, Abscess and Subgingival plaque. The involved functions are known as Biochemical Reaction, 5-(carboxyamino)imidazole ribonucleotide mutase activity, nitrate reductase activity, urease activity and colony morphology. Isovaleric acid often locates in Skeleton, Abdomen, Chromosomes, Tissue membrane and Microsomes. The associated genes with ISOVALERIC ACID are trypticase, Operon, KCNT1 gene, Genome and Reverse primer. The related lipids are Fatty Acids, Propionate, Fatty Acids, Unsaturated, Steroids and Promega. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of ISOVALERIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ISOVALERIC ACID?

ISOVALERIC ACID is suspected in Exanthema, Isovaleryl-CoA dehydrogenase deficiency, Subgingival plaque, Dehydration, MAJOR DEPRESSIVE DISORDER 1, MAJOR DEPRESSIVE DISORDER 2 and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ISOVALERIC ACID

MeSH term MeSH ID Detail
Inflammatory Bowel Diseases D015212 9 associated lipids
Occupational Diseases D009784 42 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Olfaction Disorders D000857 17 associated lipids
Maple Syrup Urine Disease D008375 5 associated lipids
Acidosis, Renal Tubular D000141 4 associated lipids
Fanconi Syndrome D005198 4 associated lipids
Lipid Metabolism, Inborn Errors D008052 26 associated lipids
Dwarfism D004392 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with ISOVALERIC ACID

Lipid pathways are not clear in current pathway databases. We organized associated pathways with ISOVALERIC ACID through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ISOVALERIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with ISOVALERIC ACID?


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Function Cross reference Weighted score Related literatures

What lipids are associated with ISOVALERIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with ISOVALERIC ACID?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ISOVALERIC ACID?

Knock-out

Knock-out are used in the study '3-Hydroxy-3-methylglutaryl-coenzyme A (CoA) synthase is involved in biosynthesis of isovaleryl-CoA in the myxobacterium Myxococcus xanthus during fruiting body formation.' (Bode HB et al., 2006) and Knock-out are used in the study 'Ethanol hypersensitivity and olfactory discrimination defect in mice lacking a homolog of Drosophila neuralized.' (Ruan Y et al., 2001).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with ISOVALERIC ACID

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Authors Title Published Journal PubMed Link
Paczkowski S and Schütz S Post-mortem volatiles of vertebrate tissue. 2011 Appl. Microbiol. Biotechnol. pmid:21720824
Kumar PA et al. Identification of fruity aroma-producing compounds from Chryseobacterium sp. isolated from the Western Ghats, India. 2011 Curr. Microbiol. pmid:21667308
Serrazanetti DI et al. Acid stress-mediated metabolic shift in Lactobacillus sanfranciscensis LSCE1. 2011 Appl. Environ. Microbiol. pmid:21335381
Shank RA et al. Current and future experimental strategies for structural analysis of trichothecene mycotoxins--a prospectus. 2011 Toxins (Basel) pmid:22295175
Pelchat ML et al. Excretion and perception of a characteristic odor in urine after asparagus ingestion: a psychophysical and genetic study. 2011 Chem. Senses pmid:20876394
Dinarvand R et al. Polylactide-co-glycolide nanoparticles for controlled delivery of anticancer agents. 2011 Int J Nanomedicine pmid:21720501
Gronow S et al. Complete genome sequence of Bacteroides salanitronis type strain (BL78). 2011 Stand Genomic Sci pmid:21677856
Hansen CF et al. A high dietary concentration of inulin is necessary to reduce the incidence of swine dysentery in pigs experimentally challenged with Brachyspira hyodysenteriae. 2011 Br. J. Nutr. pmid:21736788
AbuGhazaleh AA et al. The effect of replacing corn with glycerol on ruminal bacteria in continuous culture fermenters. 2011 J Anim Physiol Anim Nutr (Berl) pmid:20880288
Göker M et al. Complete genome sequence of Odoribacter splanchnicus type strain (1651/6). 2011 Stand Genomic Sci pmid:21677857