Cardamonin is a lipid of Polyketides (PK) class. Cardamonin is associated with abnormalities such as Septicemia, endothelial dysfunction, Hypertensive disease, Morphologically altered structure and Disintegration. The involved functions are known as Phosphorylation, Transcriptional Activation, Cell secretion, Canonical Wnt Signaling Pathway and Signal Transduction. Cardamonin often locates in Extracellular, Body tissue, IkappaB kinase complex, Membrane and Muscle, Smooth, Vascular. The associated genes with Cardamonin are ITLN1 gene, Candidate Disease Gene, MTPN gene, Genes, Reporter and PTGS2 gene. The related lipids are Lipopolysaccharides.
To understand associated biological information of Cardamonin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Cardamonin is suspected in Hypertensive disease, Septicemia, endothelial dysfunction, Morphologically altered structure, Disintegration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Cardamonin
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Neoplasm Invasiveness | D009361 | 23 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang S et al. | Cardamonin, a Novel Antagonist of hTRPA1 Cation Channel, Reveals Therapeutic Mechanism of Pathological Pain. | 2016 | Molecules | pmid:27589700 |
| Jia D et al. | Cardamonin reduces chemotherapy-enriched breast cancer stem-like cells in vitro and in vivo. | 2016 | Oncotarget | pmid:26506421 |
| Xue ZG et al. | Cardamonin Inhibits Angiogenesis by mTOR Downregulation in SKOV3 Cells. | 2016 | Planta Med. | pmid:26393941 |
| de Castro CC et al. | Cardamonin, a schistosomicidal chalcone from Piper aduncum L. (Piperaceae) that inhibits Schistosoma mansoni ATP diphosphohydrolase. | 2015 | Phytomedicine | pmid:26321741 |
| Jiang FS et al. | Cardamonin Regulates miR-21 Expression and Suppresses Angiogenesis Induced by Vascular Endothelial Growth Factor. | 2015 | Biomed Res Int | pmid:26266258 |
| Ren G et al. | The anti-inflammatory effect and potential mechanism of cardamonin in DSS-induced colitis. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:26251468 |
| Wu N et al. | Cardamonin induces apoptosis by suppressing STAT3 signaling pathway in glioblastoma stem cells. | 2015 | Tumour Biol. | pmid:26150336 |
| Kim YJ et al. | Cardamonin induces autophagy and an antiproliferative effect through JNK activation in human colorectal carcinoma HCT116 cells. | 2015 | Bioorg. Med. Chem. Lett. | pmid:25959811 |
| Jaiswal S et al. | Gender-related pharmacokinetics and bioavailability of a novel anticancer chalcone, cardamonin, in rats determined by liquid chromatography tandem mass spectrometry. | 2015 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:25703949 |
| Li YY et al. | Anti-inflammatory activities of cardamonin from Alpinia katsumadai through heme oxygenase-1 induction and inhibition of NF-κB and MAPK signaling pathway in the carrageenan-induced paw edema. | 2015 | Int. Immunopharmacol. | pmid:25681284 |