|MeSH term||MeSH ID||Detail|
|Melanoma||D008545||69 associated lipids|
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
|Disease||Cross reference||Weighted score||Related literature|
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
|Pathway name||Related literatures|
Associated locations are in red color. Not associated locations are in black.
|Location||Cross reference||Weighted score||Related literatures|
|Function||Cross reference||Weighted score||Related literatures|
|Lipid concept||Cross reference||Weighted score||Related literatures|
|Gene||Cross reference||Weighted score||Related literatures|
There are no associated biomedical information in the current reference collection.
|Liu YL et al.||Taxodione and arenarone inhibit farnesyl diphosphate synthase by binding to the isopentenyl diphosphate site.||2014||Proc. Natl. Acad. Sci. U.S.A.||pmid:24927548|
|Xi Y et al.||[Amplification efficency and optimization of culture conditions of Î³Î´ T cells in peripheral blood by different phosphate compounds].||2014||Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi||pmid:25108442|
|Bowman JD et al.||Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box.||2014||Antimicrob. Agents Chemother.||pmid:24247137|
|Mannen K et al.||Coordinated transcriptional regulation of isopentenyl diphosphate biosynthetic pathway enzymes in plastids by phytochrome-interacting factor 5.||2014||Biochem. Biophys. Res. Commun.||pmid:24342623|
|Saxena B et al.||Metabolic engineering of chloroplasts for artemisinic acid biosynthesis and impact on plant growth.||2014||J. Biosci.||pmid:24499788|
|Bentinger M et al.||Effects of various squalene epoxides on coenzyme Q and cholesterol synthesis.||2014||Biochim. Biophys. Acta||pmid:24747199|
|Banerjee A and Sharkey TD||Methylerythritol 4-phosphate (MEP) pathway metabolic regulation.||2014||Nat Prod Rep||pmid:24921065|
|Laurent AJ et al.||Synergistic effects of ethanol and isopentenyl pyrophosphate on expansion of Î³Î´ T cells in synovial fluid from patients with arthritis.||2014||PLoS ONE||pmid:25090614|
|Teufel R et al.||One-pot enzymatic synthesis of merochlorin A and B.||2014||Angew. Chem. Int. Ed. Engl.||pmid:25115835|
|Fox DT et al.||Sub-inhibitory fosmidomycin exposures elicits oxidative stress in Salmonella enterica serovar Typhimurium LT2.||2014||PLoS ONE||pmid:24751777|