(-)-Perillyl alcohol

(-)-perillyl alcohol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Cell Cycle Progression, Cell Cycle, Cell Proliferation, Apoptosis and Isoprenylation. (-)-perillyl alcohol often locates in Cytoplasm, Membrane and Plasma membrane. The associated genes with (-)-Perillyl alcohol are JUN gene, Candidate Disease Gene, IL24 gene, BCL2L1 gene and CFB gene. The related experimental models are Transgenic Model.

Cross Reference

Introduction

To understand associated biological information of (-)-Perillyl alcohol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Perillyl alcohol?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Perillyl alcohol

MeSH term MeSH ID Detail
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Esophageal Neoplasms D004938 20 associated lipids
Precancerous Conditions D011230 48 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Brain Neoplasms D001932 15 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with (-)-Perillyl alcohol

Lipid pathways are not clear in current pathway databases. We organized associated pathways with (-)-Perillyl alcohol through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Perillyl alcohol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with (-)-Perillyl alcohol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Perillyl alcohol?

There are no associated biomedical information in the current reference collection.

What genes are associated with (-)-Perillyl alcohol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Perillyl alcohol?

Transgenic Model

Transgenic Model are used in the study 'A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.' (Stratton SP et al., 2010).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with (-)-Perillyl alcohol

Download all related citations
Per page 10 20 50 100 | Total 165
Authors Title Published Journal PubMed Link
Sultana S et al. Perillyl alcohol as a protective modulator against rat hepatocarcinogenesis via amelioration of oxidative damage and cell proliferation. 2013 Hum Exp Toxicol pmid:23536516
Sundin T et al. eIF4E-Overexpression imparts perillyl alcohol and rapamycin-mediated regulation of telomerase reverse transcriptase. 2013 Exp. Cell Res. pmid:23747720
Silva MM et al. Influence of GSTM1 and GSTT1 polymorphisms on the survival rate of patients with malignant glioma under perillyl alcohol-based therapy. 2013 Genet. Mol. Res. pmid:23765968
Farazuddin M et al. Anticancer efficacy of perillyl alcohol-bearing PLGA microparticles. 2012 Int J Nanomedicine pmid:22275821
Jung HJ et al. Calcium blockers decrease the bortezomib resistance in mantle cell lymphoma via manipulation of tissue transglutaminase activities. 2012 Blood pmid:22294726
Cho HY et al. Perillyl alcohol for the treatment of temozolomide-resistant gliomas. 2012 Mol. Cancer Ther. pmid:22933703
da Silveira Fd et al. Analysis of EGF+61A>G polymorphism and EGF serum levels in Brazilian glioma patients treated with perillyl alcohol-based therapy. 2012 J. Cancer Res. Clin. Oncol. pmid:22481252
Sundin T et al. The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells. 2012 Biochimie pmid:22902867
Duelund L et al. Influence of the active compounds of Perilla frutescens leaves on lipid membranes. 2012 J. Nat. Prod. pmid:22272932
Seifert A et al. An efficient route to selective bio-oxidation catalysts: an iterative approach comprising modeling, diversification, and screening, based on CYP102A1. 2011 Chembiochem pmid:21591046