| MeSH term | MeSH ID | Detail |
|---|---|---|
| Adenocarcinoma | D000230 | 166 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Pancreatic Neoplasms | D010190 | 77 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Esophageal Neoplasms | D004938 | 20 associated lipids |
| Precancerous Conditions | D011230 | 48 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Brain Neoplasms | D001932 | 15 associated lipids |
(-)-Perillyl alcohol
(-)-perillyl alcohol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Cell Cycle Progression, Cell Cycle, Cell Proliferation, Apoptosis and Isoprenylation. (-)-perillyl alcohol often locates in Cytoplasm, Membrane and Plasma membrane. The associated genes with (-)-Perillyl alcohol are JUN gene, Candidate Disease Gene, IL24 gene, BCL2L1 gene and CFB gene. The related experimental models are Transgenic Model.
Cross Reference
Introduction
To understand associated biological information of (-)-Perillyl alcohol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with (-)-Perillyl alcohol?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with (-)-Perillyl alcohol
PubChem Associated disorders and diseases
What pathways are associated with (-)-Perillyl alcohol
Lipid pathways are not clear in current pathway databases. We organized associated pathways with (-)-Perillyl alcohol through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with (-)-Perillyl alcohol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with (-)-Perillyl alcohol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with (-)-Perillyl alcohol?
There are no associated biomedical information in the current reference collection.
What genes are associated with (-)-Perillyl alcohol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with (-)-Perillyl alcohol?
Transgenic Model
Transgenic Model are used in the study 'A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer.' (Stratton SP et al., 2010).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with (-)-Perillyl alcohol
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Stratton SP et al. | A phase 2a study of topical perillyl alcohol cream for chemoprevention of skin cancer. | 2010 | Cancer Prev Res (Phila) | pmid:20103724 |
| Clifford JL and DiGiovanni J | The promise of natural products for blocking early events in skin carcinogenesis. | 2010 | Cancer Prev Res (Phila) | pmid:20103730 |
| Chaudhary SC et al. | Perillyl alcohol attenuates Ras-ERK signaling to inhibit murine skin inflammation and tumorigenesis. | 2009 | Chem. Biol. Interact. | pmid:19161993 |
| Da Fonseca CO et al. | Correlation of tumor topography and peritumoral edema of recurrent malignant gliomas with therapeutic response to intranasal administration of perillyl alcohol. | 2009 | Invest New Drugs | pmid:19139816 |
| Magkouta S et al. | Protective effects of mastic oil from Pistacia lentiscus variation chia against experimental growth of lewis lung carcinoma. | 2009 | Nutr Cancer | pmid:19838938 |
| Zhou W et al. | Components of lemon essential oil attenuate dementia induced by scopolamine. | 2009 | Nutr Neurosci | pmid:19356307 |
| Kim D and Ortiz de Montellano PR | Tricistronic overexpression of cytochrome P450cam, putidaredoxin, and putidaredoxin reductase provides a useful cell-based catalytic system. | 2009 | Biotechnol. Lett. | pmid:19458919 |
| da Fonseca CO et al. | Ras pathway activation in gliomas: a strategic target for intranasal administration of perillyl alcohol. | 2008 Jul-Aug | Arch. Immunol. Ther. Exp. (Warsz.) | pmid:18726148 |
| Bailey HH et al. | Phase II trial of daily oral perillyl alcohol (NSC 641066) in treatment-refractory metastatic breast cancer. | 2008 | Cancer Chemother. Pharmacol. | pmid:17885756 |
| da Fonseca CO et al. | Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas. | 2008 | Surg Neurol | pmid:18295834 |