| MeSH term | MeSH ID | Detail |
|---|---|---|
| Uremia | D014511 | 33 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Ketosis | D007662 | 13 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Carbon Tetrachloride Poisoning | D002252 | 12 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Prostatic Neoplasms | D011471 | 126 associated lipids |
| Weight Gain | D015430 | 101 associated lipids |
| Glioma | D005910 | 112 associated lipids |
3-Methyl-2-oxobutanoic acid
3-Methyl-2-oxobutanoic acid is a lipid of Fatty Acyls (FA) class. 3-methyl-2-oxobutanoic acid is associated with abnormalities such as Maple Syrup Urine Disease and Kidney Failure, Chronic. The involved functions are known as Phosphorylation, Citric Acid Cycle, inhibitors, Process and Metabolic Control. 3-methyl-2-oxobutanoic acid often locates in Mitochondria, BL21, Cytoplasm, Ribosomes and Head. The associated genes with 3-Methyl-2-oxobutanoic acid are Genome, Homologous Gene, Operon, Alleles and Oxidoreductase Gene. The related lipids are dimyristoylphosphatidylglycerol, 9-oxononanoic acid, Valerates and alpha-ketocaproic acid.
Cross Reference
Introduction
To understand associated biological information of 3-Methyl-2-oxobutanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 3-Methyl-2-oxobutanoic acid?
3-Methyl-2-oxobutanoic acid is suspected in Maple Syrup Urine Disease, Kidney Failure, Chronic and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 3-Methyl-2-oxobutanoic acid
PubChem Associated disorders and diseases
What pathways are associated with 3-Methyl-2-oxobutanoic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 3-Methyl-2-oxobutanoic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 3-Methyl-2-oxobutanoic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 3-Methyl-2-oxobutanoic acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 3-Methyl-2-oxobutanoic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 3-Methyl-2-oxobutanoic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 3-Methyl-2-oxobutanoic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Saylor PJ et al. | Prospective study of changes in the metabolomic profiles of men during their first three months of androgen deprivation therapy for prostate cancer. | 2012 | Clin. Cancer Res. | pmid:22589396 |
| Jia X et al. | Engineering a metabolic pathway for isobutanol biosynthesis in Bacillus subtilis. | 2012 | Appl. Biochem. Biotechnol. | pmid:21537892 |
| Gutsche KA et al. | Production of volatile compounds by Lactobacillus sakei from branched chain α-keto acids. | 2012 | Food Microbiol. | pmid:22202876 |
| Li S et al. | Improved 2-methyl-1-propanol production in an engineered Bacillus subtilis by constructing inducible pathways. | 2012 | Biotechnol. Lett. | pmid:22941373 |
| Lamsen EN and Atsumi S | Recent progress in synthetic biology for microbial production of C3-C10 alcohols. | 2012 | Front Microbiol | pmid:22701113 |
| Ensminger AW et al. | Experimental evolution of Legionella pneumophila in mouse macrophages leads to strains with altered determinants of environmental survival. | 2012 | PLoS Pathog. | pmid:22693450 |
| Liu Z et al. | Complete Genome of Ignavibacterium album, a Metabolically Versatile, Flagellated, Facultative Anaerobe from the Phylum Chlorobi. | 2012 | Front Microbiol | pmid:22661972 |
| Zhou M et al. | Tissue-specific and nutrient regulation of the branched-chain α-keto acid dehydrogenase phosphatase, protein phosphatase 2Cm (PP2Cm). | 2012 | J. Biol. Chem. | pmid:22589535 |
| Zhang D et al. | A novel ion-pair RP-HPLC method for determination of five components in compound α-ketoacid tablets. | 2012 | J Pharm Biomed Anal | pmid:22510314 |
| Wang YP et al. | Two novel mutations in the BCKDHB gene (R170H, Q346R) cause the classic form of maple syrup urine disease (MSUD). | 2012 | Gene | pmid:22326532 |