MeSH term | MeSH ID | Detail |
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Limb Deformities, Congenital | D017880 | 4 associated lipids |
Zymosterol is a lipid of Sterol Lipids (ST) class. Zymosterol is associated with abnormalities such as Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease and Virus Diseases. The involved functions are known as Process, enzyme activity, Anabolism, Transcription, Genetic and Synthesis. Zymosterol often locates in Cytosol, Mitochondria, Articular system, Protoplasm and Tissue membrane. The associated genes with Zymosterol are Genome, Homologous Gene, Amino Acids, Acidic, Peptide Fragments and DLC1 gene. The related lipids are zymosterol, Cardiolipins, 25-azacholesterol, Sterols and Steroids. The related experimental models are Knock-out.
To understand associated biological information of Zymosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Zymosterol is suspected in Leishmaniasis, Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease, Virus Diseases and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Zymosterol
MeSH term | MeSH ID | Detail |
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Limb Deformities, Congenital | D017880 | 4 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Knock-out are used in the study 'Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major.' (Chavali AK et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ganapathy K et al. | Purification, characterization and inhibition of sterol C24-methyltransferase from Candida albicans. | 2011 | Arch. Biochem. Biophys. | pmid:20946868 |
Jokela H et al. | Hydroxysteroid (17beta) dehydrogenase 7 activity is essential for fetal de novo cholesterol synthesis and for neuroectodermal survival and cardiovascular differentiation in early mouse embryos. | 2010 | Endocrinology | pmid:20185768 |
Fon Tacer K et al. | Adaptation of cholesterol synthesis to fasting and TNF-alpha: profiling cholesterol intermediates in the liver, brain, and testis. | 2010 | J. Steroid Biochem. Mol. Biol. | pmid:20206258 |
Kawashima H et al. | Differences in sterol composition between male and female gonads of dominant limpet species. | 2009 | Lipids | pmid:19452182 |
de Souza W and Rodrigues JC | Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs. | 2009 | Interdiscip Perspect Infect Dis | pmid:19680554 |
Leszczynska A et al. | Investigating the effects of statins on cellular lipid metabolism using a yeast expression system. | 2009 | PLoS ONE | pmid:20041128 |
Nes WD et al. | Sterol 24-C-methyltransferase: an enzymatic target for the disruption of ergosterol biosynthesis and homeostasis in Cryptococcus neoformans. | 2009 | Arch. Biochem. Biophys. | pmid:19014901 |
Acimovic J et al. | Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19525158 |
Ishida K et al. | Growth inhibition and ultrastructural alterations induced by Delta24(25)-sterol methyltransferase inhibitors in Candida spp. isolates, including non-albicans organisms. | 2009 | BMC Microbiol. | pmid:19379501 |
Rintala E et al. | Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae. | 2009 | BMC Genomics | pmid:19804647 |