Zymosterol

Zymosterol is a lipid of Sterol Lipids (ST) class. Zymosterol is associated with abnormalities such as Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease and Virus Diseases. The involved functions are known as Process, enzyme activity, Anabolism, Transcription, Genetic and Synthesis. Zymosterol often locates in Cytosol, Mitochondria, Articular system, Protoplasm and Tissue membrane. The associated genes with Zymosterol are Genome, Homologous Gene, Amino Acids, Acidic, Peptide Fragments and DLC1 gene. The related lipids are zymosterol, Cardiolipins, 25-azacholesterol, Sterols and Steroids. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of Zymosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Zymosterol?

Zymosterol is suspected in Leishmaniasis, Congenital Abnormality, Coronary Arteriosclerosis, Liver diseases, Alzheimer's Disease, Virus Diseases and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Zymosterol

MeSH term MeSH ID Detail
Limb Deformities, Congenital D017880 4 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Zymosterol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Zymosterol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Zymosterol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Zymosterol?

Related references are published most in these journals:

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What genes are associated with Zymosterol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Zymosterol?

Knock-out

Knock-out are used in the study 'Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major.' (Chavali AK et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Zymosterol

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Authors Title Published Journal PubMed Link
Nes WD et al. Sterol 24-C-methyltransferase: an enzymatic target for the disruption of ergosterol biosynthesis and homeostasis in Cryptococcus neoformans. 2009 Arch. Biochem. Biophys. pmid:19014901
Nes WD et al. Yeast sterol C24-methyltransferase: role of highly conserved tyrosine-81 in catalytic competence studied by site-directed mutagenesis and thermodynamic analysis. 2008 Arch. Biochem. Biophys. pmid:18555004
Snitkin ES et al. Model-driven analysis of experimentally determined growth phenotypes for 465 yeast gene deletion mutants under 16 different conditions. 2008 Genome Biol. pmid:18808699
Andersen MR et al. Metabolic model integration of the bibliome, genome, metabolome and reactome of Aspergillus niger. 2008 Mol. Syst. Biol. pmid:18364712
Chavali AK et al. Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major. 2008 Mol. Syst. Biol. pmid:18364711
Vinci G et al. Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses. 2008 PLoS ONE pmid:18682733
Iwaki T et al. Multiple functions of ergosterol in the fission yeast Schizosaccharomyces pombe. 2008 Microbiology (Reading, Engl.) pmid:18310029
Cushion MT et al. Transcriptome of Pneumocystis carinii during fulminate infection: carbohydrate metabolism and the concept of a compatible parasite. 2007 PLoS ONE pmid:17487271
Megha O et al. Cholesterol precursors stabilize ordinary and ceramide-rich ordered lipid domains (lipid rafts) to different degrees. Implications for the Bloch hypothesis and sterol biosynthesis disorders. 2006 J. Biol. Chem. pmid:16735517
Yang C et al. Sterol intermediates from cholesterol biosynthetic pathway as liver X receptor ligands. 2006 J. Biol. Chem. pmid:16857673