Coprosterol is a lipid of Sterol Lipids (ST) class. Coprosterol is associated with abnormalities such as Cerebrovascular accident, Glycogen Storage Disease Type IV, Coronary Arteriosclerosis, CARDIAC EVENT and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as cholesterol absorption, Death, Sudden, Cardiac, Drug Interactions, Cholesterol Homeostasis and Synthesis. Coprosterol often locates in lipid raft, Tissue membrane, Membrane, Blood and Body tissue. The associated genes with Coprosterol are ABO gene, STN gene, Alleles, Apolipoprotein E gene and TNF gene. The related lipids are saturated fat, campesterol, lathosterol, Sterols and Total cholesterol. The related experimental models are Rodent Model.
To understand associated biological information of Coprosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Coprosterol is suspected in Coronary Arteriosclerosis, Cerebrovascular accident, Glycogen Storage Disease Type IV, CARDIAC EVENT, Diabetes Mellitus, Non-Insulin-Dependent, Niemann-Pick Diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Coprosterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Cataract | D002386 | 34 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Alcoholism | D000437 | 27 associated lipids |
| Brain Diseases, Metabolic | D001928 | 9 associated lipids |
| Biliary Fistula | D001658 | 13 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Xanthomatosis, Cerebrotendinous | D019294 | 14 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
Rodent Model are used in the study 'Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome.' (Keller RK et al., 2004).
| Model | Cross reference | Weighted score | Related literatures |
|---|
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Devane ML et al. | Identifying avian sources of faecal contamination using sterol analysis. | 2015 | Environ Monit Assess | pmid:26370196 |
| Wang X et al. | Plasma cholesterol-lowering activity of dietary dihydrocholesterol in hypercholesterolemia hamsters. | 2015 | Atherosclerosis | pmid:26184696 |
| Aoki K et al. | Anagliptin decreases serum lathosterol level in patients with type 2 diabetes: a pilot study. | 2015 | Expert Opin Pharmacother | pmid:26098722 |
| Moraes EA et al. | Cholestanol-loaded-cyclodextrin improves the quality of stallion spermatozoa after cryopreservation. | 2015 | Anim. Reprod. Sci. | pmid:26005214 |
| Luister A et al. | Increased plant sterol deposition in vascular tissue characterizes patients with severe aortic stenosis and concomitant coronary artery disease. | 2015 | Steroids | pmid:25814070 |
| Benesch MG et al. | A DSC and FTIR spectroscopic study of the effects of the epimeric coprostan-3-ols and coprostan-3-one on the thermotropic phase behaviour and organization of dipalmitoylphosphatidylcholine bilayer membranes: Comparison with their 5-cholesten analogues. | 2015 | Chem. Phys. Lipids | pmid:25804450 |
| Mutanen A et al. | Serum plant sterols, cholestanol, and cholesterol precursors associate with histological liver injury in pediatric onset intestinal failure. | 2014 | Am. J. Clin. Nutr. | pmid:25099547 |
| Harrault L et al. | Are fecal stanols suitable to record and identify a pulse of human fecal contamination in short-term exposed shellfish? A microcosm study. | 2014 | Mar. Pollut. Bull. | pmid:25455370 |
| Tolosa I et al. | Steroid markers to assess sewage and other sources of organic contaminants in surface sediments of Cienfuegos Bay, Cuba. | 2014 | Mar. Pollut. Bull. | pmid:25127498 |
| Yoshinaga T et al. | Clinical and radiological findings of a cerebrotendinous xanthomatosis patient with a novel p.A335V mutation in the CYP27A1 gene. | 2014 | Intern. Med. | pmid:25447658 |