22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Takahashi K et al. | Metabolic conversion of 24-methyl-Delta25-cholesterol to 24-methylcholesterol in higher plants. | 2006 | Bioorg. Med. Chem. | pmid:16213729 |
| Sabudak T et al. | Potent tyrosinase inhibitors from Trifolium balansae. | 2006 | Nat. Prod. Res. | pmid:16901809 |
| Takahashi K et al. | Purification and ATPase activity of human ABCA1. | 2006 | J. Biol. Chem. | pmid:16500904 |
| de Jong A et al. | Plant sterol or stanol consumption does not affect erythrocyte osmotic fragility in patients on statin treatment. | 2006 | Eur J Clin Nutr | pmid:16482072 |
| Oswald S et al. | Disposition and sterol-lowering effect of ezetimibe are influenced by single-dose coadministration of rifampin, an inhibitor of multidrug transport proteins. | 2006 | Clin. Pharmacol. Ther. | pmid:17112804 |
| Yokosuka A et al. | New glycosides of the campesterol derivative from the rhizomes of Tacca chantrieri. | 2005 | Steroids | pmid:15784281 |
| Conchillo A et al. | Levels of phytosterol oxides in enriched and nonenriched spreads: application of a thin-layer chromatography-gas chromatography methodology. | 2005 | J. Agric. Food Chem. | pmid:16190640 |
| Päivä H et al. | High-dose statins and skeletal muscle metabolism in humans: a randomized, controlled trial. | 2005 | Clin. Pharmacol. Ther. | pmid:16003294 |
| Ho SS and Pal S | Margarine phytosterols decrease the secretion of atherogenic lipoproteins from HepG2 liver and Caco2 intestinal cells. | 2005 | Atherosclerosis | pmid:16115472 |
| Awad AB et al. | beta-Sitosterol stimulates ceramide metabolism in differentiated Caco2 cells. | 2005 | J. Nutr. Biochem. | pmid:16098730 |