22,23-dihydrobrassicasterol is a lipid of Sterol Lipids (ST) class. 22,23-dihydrobrassicasterol is associated with abnormalities such as Diabetes, Macular degeneration, Drusen, Systemic disease and Diabetes Mellitus. The involved functions are known as cholesterol metabolism, Synthesis, Intestinal Absorption, Liver function and cholesterol absorption. 22,23-dihydrobrassicasterol often locates in Back and Cell membrane. The associated genes with 22,23-dihydrobrassicasterol are apolipoprotein E-3. The related lipids are Total cholesterol, campesterol, lathosterol, Fatty Acids, Nonesterified and Cholesterol, Dietary.
To understand associated biological information of 22,23-dihydrobrassicasterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
22,23-dihydrobrassicasterol is suspected in Diabetes, Macular degeneration, Drusen, Systemic disease, Diabetes Mellitus, Liver diseases and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 22,23-dihydrobrassicasterol
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Disease | D003327 | 70 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Hyperlipoproteinemia Type II | D006938 | 22 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypolipoproteinemias | D007009 | 9 associated lipids |
| Xanthomatosis | D014973 | 17 associated lipids |
| Metabolic Syndrome | D024821 | 44 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
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| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nes WD | Biosynthesis of cholesterol and other sterols. | 2011 | Chem. Rev. | pmid:21902244 |
| Labonté MÈ et al. | Comparison of the impact of trans fatty acids from ruminant and industrial sources on surrogate markers of cholesterol homeostasis in healthy men. | 2011 | Mol Nutr Food Res | pmid:21656668 |
| Gälman C et al. | Pronounced variation in bile acid synthesis in humans is related to gender, hypertriglyceridaemia and circulating levels of fibroblast growth factor 19. | 2011 | J. Intern. Med. | pmid:22003820 |
| Schröder M and Vetter W | High-speed counter-current chromatographic separation of phytosterols. | 2011 | Anal Bioanal Chem | pmid:21499948 |
| Husche C et al. | Validation of an isotope dilution gas chromatography-mass spectrometry method for analysis of 7-oxygenated campesterol and sitosterol in human serum. | 2011 | Chem. Phys. Lipids | pmid:21620808 |
| Ramos SC et al. | The role of soluble fiber intake in patients under highly effective lipid-lowering therapy. | 2011 | Nutr J | pmid:21810257 |
| Kurvinen A et al. | Effects of long-term parenteral nutrition on serum lipids, plant sterols, cholesterol metabolism, and liver histology in pediatric intestinal failure. | 2011 | J. Pediatr. Gastroenterol. Nutr. | pmid:21543999 |
| Valitova JN et al. | Effects of sterol-binding agent nystatin on wheat roots: the changes in membrane permeability, sterols and glycoceramides. | 2011 | Phytochemistry | pmid:21726881 |
| Hernández-Mijares A et al. | Low intestinal cholesterol absorption is associated with a reduced efficacy of phytosterol esters as hypolipemic agents in patients with metabolic syndrome. | 2011 | Clin Nutr | pmid:21489663 |
| Noto D et al. | Plasma non-cholesterol sterols in primary hypobetalipoproteinemia. | 2011 | Atherosclerosis | pmid:21492858 |