2-Hydroxyestrone

2-hydroxyestrone is a lipid of Sterol Lipids (ST) class. 2-hydroxyestrone is associated with abnormalities such as Consumption-archaic term for TB and Estrogenic effect. The involved functions are known as Excretory function, Estrogen Metabolic Process, Urinary concentration, Biochemical Pathway and Cell Proliferation. 2-hydroxyestrone often locates in Mammary Gland Parenchyma. The associated genes with 2-Hydroxyestrone are CYP17A1 gene, CYP1A2 gene, SHBG gene and Alleles. The related lipids are 16-ketoestradiol and 4-methoxyestradiol.

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Introduction

To understand associated biological information of 2-Hydroxyestrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2-Hydroxyestrone?

2-Hydroxyestrone is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-Hydroxyestrone

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with 2-Hydroxyestrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2-Hydroxyestrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2-Hydroxyestrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2-Hydroxyestrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2-Hydroxyestrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2-Hydroxyestrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2-Hydroxyestrone

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Authors Title Published Journal PubMed Link
Dunlap TL et al. Red Clover Aryl Hydrocarbon Receptor (AhR) and Estrogen Receptor (ER) Agonists Enhance Genotoxic Estrogen Metabolism. 2017 Chem. Res. Toxicol. pmid:28985473
Gao WL et al. Measurement of serum estrogen and estrogen metabolites in pre- and postmenopausal women with osteoarthritis using high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry. 2015 Braz. J. Med. Biol. Res. pmid:25410577
Dikshit A et al. Flaxseed reduces the pro-carcinogenic micro-environment in the ovaries of normal hens by altering the PG and oestrogen pathways in a dose-dependent manner. 2015 Br. J. Nutr. pmid:25850566
Gheldiu AM et al. Oxidative Metabolism of Estrone Modified by Genistein and Bisphenol A in Rat Liver Microsomes. 2015 Biomed. Environ. Sci. pmid:26695363
Telang N et al. Comparative efficacy of extracts from Lycium barbarum bark and fruit on estrogen receptor positive human mammary carcinoma MCF-7 cells. 2014 Nutr Cancer pmid:24377707
Godínez Martínez EY et al. [Determination of 2-hydroxyestrone /16α-hydroxyestrone ratio in urine of Mexican women as a risk indicator for breast cancer and its relationship with other risk factors]. 2014 Nutr Hosp pmid:25617571
Arslan AA et al. Circulating estrogen metabolites and risk of breast cancer in postmenopausal women. 2014 Cancer Epidemiol. Biomarkers Prev. pmid:24769889
Bazzan AJ et al. Multi-nutrient supplement improves hormone ratio associated with cancer risk. 2013 J Transl Med pmid:24103703
Morimoto Y et al. Urinary estrogen metabolites during a randomized soy trial. 2012 Nutr Cancer pmid:22293063
Maskarinec G et al. The relation of urinary estrogen metabolites with mammographic densities in premenopausal women. 2012 Cancer Epidemiol pmid:22537763