MeSH term | MeSH ID | Detail |
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Body Weight | D001835 | 333 associated lipids |
2-hydroxyestrone is a lipid of Sterol Lipids (ST) class. 2-hydroxyestrone is associated with abnormalities such as Consumption-archaic term for TB and Estrogenic effect. The involved functions are known as Excretory function, Estrogen Metabolic Process, Urinary concentration, Biochemical Pathway and Cell Proliferation. 2-hydroxyestrone often locates in Mammary Gland Parenchyma. The associated genes with 2-Hydroxyestrone are CYP17A1 gene, CYP1A2 gene, SHBG gene and Alleles. The related lipids are 16-ketoestradiol and 4-methoxyestradiol.
To understand associated biological information of 2-Hydroxyestrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
2-Hydroxyestrone is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 2-Hydroxyestrone
MeSH term | MeSH ID | Detail |
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Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Dunlap TL et al. | Red Clover Aryl Hydrocarbon Receptor (AhR) and Estrogen Receptor (ER) Agonists Enhance Genotoxic Estrogen Metabolism. | 2017 | Chem. Res. Toxicol. | pmid:28985473 |
Gao WL et al. | Measurement of serum estrogen and estrogen metabolites in pre- and postmenopausal women with osteoarthritis using high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry. | 2015 | Braz. J. Med. Biol. Res. | pmid:25410577 |
Dikshit A et al. | Flaxseed reduces the pro-carcinogenic micro-environment in the ovaries of normal hens by altering the PG and oestrogen pathways in a dose-dependent manner. | 2015 | Br. J. Nutr. | pmid:25850566 |
Gheldiu AM et al. | Oxidative Metabolism of Estrone Modified by Genistein and Bisphenol A in Rat Liver Microsomes. | 2015 | Biomed. Environ. Sci. | pmid:26695363 |
Telang N et al. | Comparative efficacy of extracts from Lycium barbarum bark and fruit on estrogen receptor positive human mammary carcinoma MCF-7 cells. | 2014 | Nutr Cancer | pmid:24377707 |
GodÃnez MartÃnez EY et al. | [Determination of 2-hydroxyestrone /16α-hydroxyestrone ratio in urine of Mexican women as a risk indicator for breast cancer and its relationship with other risk factors]. | 2014 | Nutr Hosp | pmid:25617571 |
Arslan AA et al. | Circulating estrogen metabolites and risk of breast cancer in postmenopausal women. | 2014 | Cancer Epidemiol. Biomarkers Prev. | pmid:24769889 |
Bazzan AJ et al. | Multi-nutrient supplement improves hormone ratio associated with cancer risk. | 2013 | J Transl Med | pmid:24103703 |
Morimoto Y et al. | Urinary estrogen metabolites during a randomized soy trial. | 2012 | Nutr Cancer | pmid:22293063 |
Maskarinec G et al. | The relation of urinary estrogen metabolites with mammographic densities in premenopausal women. | 2012 | Cancer Epidemiol | pmid:22537763 |