2-Hydroxyestrone

2-hydroxyestrone is a lipid of Sterol Lipids (ST) class. 2-hydroxyestrone is associated with abnormalities such as Consumption-archaic term for TB and Estrogenic effect. The involved functions are known as Excretory function, Estrogen Metabolic Process, Urinary concentration, Biochemical Pathway and Cell Proliferation. 2-hydroxyestrone often locates in Mammary Gland Parenchyma. The associated genes with 2-Hydroxyestrone are CYP17A1 gene, CYP1A2 gene, SHBG gene and Alleles. The related lipids are 16-ketoestradiol and 4-methoxyestradiol.

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Introduction

To understand associated biological information of 2-Hydroxyestrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2-Hydroxyestrone?

2-Hydroxyestrone is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-Hydroxyestrone

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with 2-Hydroxyestrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2-Hydroxyestrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2-Hydroxyestrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2-Hydroxyestrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2-Hydroxyestrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2-Hydroxyestrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2-Hydroxyestrone

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Authors Title Published Journal PubMed Link
Tam A et al. The role of female hormones on lung function in chronic lung diseases. 2011 BMC Womens Health pmid:21639909
Obi N et al. Estrogen metabolite ratio: Is the 2-hydroxyestrone to 16α-hydroxyestrone ratio predictive for breast cancer? 2011 Int J Womens Health pmid:21339936
Cleary MP and Grossmann ME The manner in which calories are restricted impacts mammary tumor cancer prevention. 2011 J Carcinog pmid:22013391
Fu L and Xu H A preliminary study of the effectiveness of chinese therapeutic food on regulating female reproductive hormones. 2011 Integr Med Insights pmid:21614163
Yu X et al. Coffee consumption and risk of cancers: a meta-analysis of cohort studies. 2011 BMC Cancer pmid:21406107
Moon YJ et al. Dietary phenethyl isothiocyanate alters gene expression in human breast cancer cells. 2011 Evid Based Complement Alternat Med pmid:20953429
Choi MH et al. Metabolic alteration of urinary steroids in pre- and post-menopausal women, and men with papillary thyroid carcinoma. 2011 BMC Cancer pmid:21824401
Gao W et al. Serum concentrations of selected endogenous estrogen and estrogen metabolites in pre- and post-menopausal Chinese women with osteoarthritis. 2010 J. Endocrinol. Invest. pmid:20339312
Laidlaw M et al. Effects of a breast-health herbal formula supplement on estrogen metabolism in pre- and post-menopausal women not taking hormonal contraceptives or supplements: a randomized controlled trial. 2010 Breast Cancer (Auckl) pmid:21234288
Sturgeon SR et al. Effect of flaxseed consumption on urinary levels of estrogen metabolites in postmenopausal women. 2010 Nutr Cancer pmid:20099191