2-Hydroxyestrone

2-hydroxyestrone is a lipid of Sterol Lipids (ST) class. 2-hydroxyestrone is associated with abnormalities such as Consumption-archaic term for TB and Estrogenic effect. The involved functions are known as Excretory function, Estrogen Metabolic Process, Urinary concentration, Biochemical Pathway and Cell Proliferation. 2-hydroxyestrone often locates in Mammary Gland Parenchyma. The associated genes with 2-Hydroxyestrone are CYP17A1 gene, CYP1A2 gene, SHBG gene and Alleles. The related lipids are 16-ketoestradiol and 4-methoxyestradiol.

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Introduction

To understand associated biological information of 2-Hydroxyestrone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2-Hydroxyestrone?

2-Hydroxyestrone is suspected in Estrogenic effect and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-Hydroxyestrone

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with 2-Hydroxyestrone

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2-Hydroxyestrone?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2-Hydroxyestrone?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2-Hydroxyestrone?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2-Hydroxyestrone?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 2-Hydroxyestrone?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2-Hydroxyestrone

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Authors Title Published Journal PubMed Link
Arslan AA et al. Circulating estrogen metabolites and risk for breast cancer in premenopausal women. 2009 Cancer Epidemiol. Biomarkers Prev. pmid:19661086
Crandall CJ et al. Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women. 2009 Breast Cancer Res. pmid:19630952
Capellino S et al. Hydroxylated estrogen metabolites influence the proliferation of cultured human monocytes: possible role in synovial tissue hyperplasia. 2008 Sep-Oct Clin. Exp. Rheumatol. pmid:19032826
Sowers MR et al. Levels of sex steroid and cardiovascular disease measures in premenopausal and hormone-treated women at midlife: implications for the "timing hypothesis". 2008 Arch. Intern. Med. pmid:18955645
Chiesa IJ et al. Contribution of alpha2-adrenoceptors to the mitogenic effect of catecholestrogen in human breast cancer MCF-7 cells. 2008 J. Steroid Biochem. Mol. Biol. pmid:18486470
Orgéas CC et al. The influence of menstrual risk factors on tumor characteristics and survival in postmenopausal breast cancer. 2008 Breast Cancer Res. pmid:19087323
Scott LM et al. Past oral contraceptive use and current dietary soy isoflavones influence estrogen metabolism in postmenopausal monkeys (Macaca fascicularis). 2008 Cancer Epidemiol. Biomarkers Prev. pmid:18843000
Jernström H et al. Coffee intake and CYP1A2*1F genotype predict breast volume in young women: implications for breast cancer. 2008 Br. J. Cancer pmid:18813311
Falk RT et al. A liquid chromatography-mass spectrometry method for the simultaneous measurement of 15 urinary estrogens and estrogen metabolites: assay reproducibility and interindividual variability. 2008 Cancer Epidemiol. Biomarkers Prev. pmid:19064556
Atkinson C et al. Daidzein-metabolizing phenotypes in relation to serum hormones and sex hormone binding globulin, and urinary estrogen metabolites in premenopausal women in the United States. 2008 Cancer Causes Control pmid:18478336