3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid is a lipid of Sterol Lipids (ST) class. 3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid is associated with abnormalities such as Cholestasis and Little's Disease. The involved functions are known as inhibitors, Signal Transduction, Phosphorylation, Cell Survival and Detergents. 3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid often locates in Protoplasm. The related lipids are Promega.
To understand associated biological information of 3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid is suspected in Cholestasis, Little's Disease and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Crohn Disease | D003424 | 12 associated lipids |
| Cholelithiasis | D002769 | 16 associated lipids |
| Blastomycosis | D001759 | 5 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Borges MM et al. | Efficacy and safety of amphotericin B deoxycholate versus N-methylglucamine antimoniate in pediatric visceral leishmaniasis: an open-label, randomized, and controlled pilot trial in Brazil. | 2017 Jan-Feb | Rev. Soc. Bras. Med. Trop. | pmid:28327804 |
| Oliveira MME et al. | Fungemia associated with Schizophyllum commune in Brazil. | 2017 | PLoS Negl Trop Dis | pmid:28662024 |
| Menotti J et al. | A cell impedance-based real-time in vitro assay to assess the toxicity of amphotericin B formulations. | 2017 | Toxicol. Appl. Pharmacol. | pmid:28865757 |
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| Grisin T et al. | Cyclodextrin-mediated self-associating chitosan micro-platelets act as a drug booster against Candida glabrata mucosal infection in immunocompetent mice. | 2017 | Int J Pharm | pmid:28130196 |
| Liu H et al. | Reduction-sensitive micelles self-assembled from amphiphilic chondroitin sulfate A-deoxycholic acid conjugate for triggered release of doxorubicin. | 2017 | Mater Sci Eng C Mater Biol Appl | pmid:28415498 |
| Khattab SN et al. | Study of antileishmanial activity of 2-aminobenzoyl amino acid hydrazides and their quinazoline derivatives. | 2017 | Bioorg. Med. Chem. Lett. | pmid:28087274 |
| Lovero G et al. | Invitro antifungal susceptibilities of Candida species to liposomal amphotericin B, determined using CLSI broth microdilution, and amphotericin B deoxycholate, measured using the Etest. | 2017 | J. Med. Microbiol. | pmid:27959780 |
| Miyamoto N et al. | A two-component micelle with emergent pH responsiveness by mixing dilauroyl phosphocholine and deoxycholic acid and its delivery of proteins into the cytosol. | 2017 | Colloids Surf B Biointerfaces | pmid:28347946 |
| Bhari N et al. | Histoplasmosis mimicking non-Hodgkin lymphoma in a 40-year-old man with AIDS. | 2017 | Int J STD AIDS | pmid:27535728 |