3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid is a lipid of Sterol Lipids (ST) class. 3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid is associated with abnormalities such as Cholestasis and Little's Disease. The involved functions are known as inhibitors, Signal Transduction, Phosphorylation, Cell Survival and Detergents. 3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid often locates in Protoplasm. The related lipids are Promega.
To understand associated biological information of 3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid is suspected in Cholestasis, Little's Disease and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 3alpha,12beta-dihydroxy-5alpha-cholan-24-oic acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Lung Neoplasms | D008175 | 171 associated lipids |
| Colonic Neoplasms | D003110 | 161 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Crohn Disease | D003424 | 12 associated lipids |
| Cholelithiasis | D002769 | 16 associated lipids |
| Blastomycosis | D001759 | 5 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Liu H et al. | Reduction-sensitive micelles self-assembled from amphiphilic chondroitin sulfate A-deoxycholic acid conjugate for triggered release of doxorubicin. | 2017 | Mater Sci Eng C Mater Biol Appl | pmid:28415498 |
| Lovero G et al. | Invitro antifungal susceptibilities of Candida species to liposomal amphotericin B, determined using CLSI broth microdilution, and amphotericin B deoxycholate, measured using the Etest. | 2017 | J. Med. Microbiol. | pmid:27959780 |
| Kim JY et al. | Selective effect of phosphatidylcholine on the lysis of adipocytes. | 2017 | PLoS ONE | pmid:28463991 |
| Shridharani SM | Early Experience in 100 Consecutive Patients With Injection Adipocytolysis for Neck Contouring With ATX-101 (Deoxycholic Acid). | 2017 | Dermatol Surg | pmid:28448317 |
| Song Y et al. | Mucormycosis in renal transplant recipients: review of 174 reported cases. | 2017 | BMC Infect. Dis. | pmid:28420334 |
| Concha-Velasco F et al. | Factors associated with early mycological clearance in HIV-associated cryptococcal meningitis. | 2017 | PLoS ONE | pmid:28355252 |
| Zhao C et al. | Discovery and Synthesis of Amino Acids Modified Deoxycholic Acid Derivatives and in Vitro Antiproliferative Evaluation. | 2017 | Chem. Pharm. Bull. | pmid:28090067 |
| Duran MI et al. | Synthesis of Five Known Brassinosteroid Analogs from Hyodeoxycholic Acid and Their Activities as Plant-Growth Regulators. | 2017 | Int J Mol Sci | pmid:28282853 |
| Miyamoto N et al. | A two-component micelle with emergent pH responsiveness by mixing dilauroyl phosphocholine and deoxycholic acid and its delivery of proteins into the cytosol. | 2017 | Colloids Surf B Biointerfaces | pmid:28347946 |
| Kobayashi Y et al. | The Associations between Circulating Bile Acids and the Muscle Volume in Patients with Non-alcoholic Fatty Liver Disease (NAFLD). | 2017 | Intern. Med. | pmid:28381740 |