15-epi-lxa4;15r-lxa4

15-epi-lxa4;15r-lxa4 is a lipid of Fatty Acyls (FA) class. 15-epi-lxa4;15r-lxa4 is associated with abnormalities such as Pneumonia, Septicemia, Cystic Fibrosis, Subarachnoid Hemorrhage and Obesity. The involved functions are known as Protective Agents, Signal Transduction, cytokine biosynthesis, Inflammation and Anabolism. 15-epi-lxa4;15r-lxa4 often locates in Blood, Immune system and Heart tissue. The associated genes with 15-epi-lxa4;15r-lxa4 are IL2 gene, CXCL13 gene and CMKLR1 gene. The related lipids are Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of 15-epi-lxa4;15r-lxa4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 15-epi-lxa4;15r-lxa4?

15-epi-lxa4;15r-lxa4 is suspected in Cystic Fibrosis, Asthma, Chagas Cardiomyopathy, Pneumonia, Septicemia, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 15-epi-lxa4;15r-lxa4

PubChem Associated disorders and diseases

What pathways are associated with 15-epi-lxa4;15r-lxa4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 15-epi-lxa4;15r-lxa4?

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What functions are associated with 15-epi-lxa4;15r-lxa4?


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What lipids are associated with 15-epi-lxa4;15r-lxa4?

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What genes are associated with 15-epi-lxa4;15r-lxa4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 15-epi-lxa4;15r-lxa4?

Knock-out

Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).

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NCBI Entrez Crosslinks

All references with 15-epi-lxa4;15r-lxa4

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Authors Title Published Journal PubMed Link
Wenceslau CF et al. Lipoxin A4 mediates aortic contraction via RHOA/RHO kinase, endothelial dysfunction and reactive oxygen species. 2014 J. Vasc. Res. pmid:25612650
Wu H et al. Lipoxin A4 and platelet activating factor are involved in E. coli or LPS-induced lung inflammation in CFTR-deficient mice. 2014 PLoS ONE pmid:24671173
Kumar R et al. Lipoxin Aâ‚„ prevents the progression of de novo and established endometriosis in a mouse model by attenuating prostaglandin Eâ‚‚ production and estrogen signaling. 2014 PLoS ONE pmid:24587003
Ramon S et al. Lipoxin Aâ‚„ modulates adaptive immunity by decreasing memory B-cell responses via an ALX/FPR2-dependent mechanism. 2014 Eur. J. Immunol. pmid:24166736
Li C et al. Estradiol and mTORC2 cooperate to enhance prostaglandin biosynthesis and tumorigenesis in TSC2-deficient LAM cells. 2014 J. Exp. Med. pmid:24395886
Ballesteros I et al. Rosiglitazone-induced CD36 up-regulation resolves inflammation by PPARγ and 5-LO-dependent pathways. 2014 J. Leukoc. Biol. pmid:24338629
Leo LM et al. Age-dependent relevance of endogenous 5-lipoxygenase derivatives in anxiety-like behavior in mice. 2014 PLoS ONE pmid:24416334
Hamza B et al. Retrotaxis of human neutrophils during mechanical confinement inside microfluidic channels. 2014 Integr Biol (Camb) pmid:24419464
Tateishi N et al. Dietary supplementation of arachidonic acid increases arachidonic acid and lipoxin Aâ‚„ contents in colon, but does not affect severity or prostaglandin Eâ‚‚ content in murine colitis model. 2014 Lipids Health Dis pmid:24507383
Ringholz FC et al. Reduced 15-lipoxygenase 2 and lipoxin A4/leukotriene B4 ratio in children with cystic fibrosis. 2014 Eur. Respir. J. pmid:24696116