| MeSH term | MeSH ID | Detail |
|---|---|---|
| Tuberculosis | D014376 | 20 associated lipids |
| Stomach Ulcer | D013276 | 75 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Lung Diseases | D008171 | 37 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Colitis | D003092 | 69 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Osteitis | D010000 | 10 associated lipids |
| Asthma | D001249 | 52 associated lipids |
15-epi-lxa4;15r-lxa4
15-epi-lxa4;15r-lxa4 is a lipid of Fatty Acyls (FA) class. 15-epi-lxa4;15r-lxa4 is associated with abnormalities such as Pneumonia, Septicemia, Cystic Fibrosis, Subarachnoid Hemorrhage and Obesity. The involved functions are known as Protective Agents, Signal Transduction, cytokine biosynthesis, Inflammation and Anabolism. 15-epi-lxa4;15r-lxa4 often locates in Blood, Immune system and Heart tissue. The associated genes with 15-epi-lxa4;15r-lxa4 are IL2 gene, CXCL13 gene and CMKLR1 gene. The related lipids are Steroids. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of 15-epi-lxa4;15r-lxa4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 15-epi-lxa4;15r-lxa4?
15-epi-lxa4;15r-lxa4 is suspected in Cystic Fibrosis, Asthma, Chagas Cardiomyopathy, Pneumonia, Septicemia, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 15-epi-lxa4;15r-lxa4
PubChem Associated disorders and diseases
What pathways are associated with 15-epi-lxa4;15r-lxa4
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 15-epi-lxa4;15r-lxa4?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 15-epi-lxa4;15r-lxa4?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 15-epi-lxa4;15r-lxa4?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 15-epi-lxa4;15r-lxa4?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 15-epi-lxa4;15r-lxa4?
Knock-out
Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with 15-epi-lxa4;15r-lxa4
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Polavarapu S et al. | Effect of polyunsaturated fatty acids and their metabolites on bleomycin-induced cytotoxic action on human neuroblastoma cells in vitro. | 2014 | PLoS ONE | pmid:25536345 |
| Zimring JC | The fat and the skinny on acute lung injury. | 2014 | Blood | pmid:25342661 |
| Martini AC et al. | Neuroprotective effects of lipoxin A4 in central nervous system pathologies. | 2014 | Biomed Res Int | pmid:25276776 |
| Zhao Q et al. | LipoxinA4 attenuates myocardial ischemia reperfusion injury via a mechanism related to downregulation of GRP-78 and caspase-12 in rats. | 2014 | Heart Vessels | pmid:24129401 |
| Ramon S et al. | Lipoxin Aâ‚„ modulates adaptive immunity by decreasing memory B-cell responses via an ALX/FPR2-dependent mechanism. | 2014 | Eur. J. Immunol. | pmid:24166736 |
| Eke Gungor H et al. | Decreased levels of lipoxin A4 and annexin A1 in wheezy infants. | 2014 | Int. Arch. Allergy Immunol. | pmid:24525704 |
| Osuchowski MF | Tender mediation in a ruthless environment: can lipoxins provide lifesaving modifications to fatally deregulated immunoinflammatory responses in sepsis?*. | 2014 | Crit. Care Med. | pmid:24633114 |
| Ueda T et al. | Combination therapy of 15-epi-lipoxin A4 with antibiotics protects mice from Escherichia coli-induced sepsis*. | 2014 | Crit. Care Med. | pmid:24463858 |
| Higgins G et al. | Activation of P2RY11 and ATP release by lipoxin A4 restores the airway surface liquid layer and epithelial repair in cystic fibrosis. | 2014 | Am. J. Respir. Cell Mol. Biol. | pmid:24588705 |
| Zhang D et al. | Glucocorticoids sensitize rat placental inflammatory responses via inhibiting lipoxin A4 biosynthesis. | 2014 | Biol. Reprod. | pmid:24571985 |