G(M3) Ganglioside

G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.

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Introduction

To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with G(M3) Ganglioside?

G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.

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PubChem Associated disorders and diseases

What pathways are associated with G(M3) Ganglioside

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with G(M3) Ganglioside?

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What functions are associated with G(M3) Ganglioside?


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What lipids are associated with G(M3) Ganglioside?

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What genes are associated with G(M3) Ganglioside?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with G(M3) Ganglioside?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with G(M3) Ganglioside

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Authors Title Published Journal PubMed Link
Coskun Ü et al. Regulation of human EGF receptor by lipids. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21571640
Inokuchi J Physiopathological function of hematoside (GM3 ganglioside). 2011 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:21558756
Garrido Arteaga R et al. Evaluation and evidence of natural gangliosides with two unsaturated bonds in the ceramide structure obtained by a combination of MALDI-MS and NMR spectroscopy. 2011 Anal Bioanal Chem pmid:21547428
Wang P et al. GM3 suppresses anchorage-independent growth via Rho GDP dissociation inhibitor beta in melanoma B16 cells. 2011 Cancer Sci. pmid:21518140
Thon V et al. PmST2: a novel Pasteurella multocida glycolipid α2-3-sialyltransferase. 2011 Glycobiology pmid:21515586
Inokuchi J Inhibition of ganglioside biosynthesis as a novel therapeutic approach in insulin resistance. 2011 Handb Exp Pharmacol pmid:21484572
Niimi K et al. Impairment of neuropsychological behaviors in ganglioside GM3-knockout mice. 2011 Biochem. Biophys. Res. Commun. pmid:21333627
Miranda A et al. Cytofluorimetric evaluation of N-glycolylated GM3 ganglioside expression on murine leukocytes. 2011 Immunol. Lett. pmid:21324343
Garbuzova-Davis S et al. Blood-brain barrier impairment in an animal model of MPS III B. 2011 PLoS ONE pmid:21408219
Hovakimyan M et al. Morphological alterations of the cornea in the mouse model of niemann-pick disease type c1. 2011 Cornea pmid:21317782