G(M3) Ganglioside

G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.

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Introduction

To understand associated biological information of G(M3) Ganglioside, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with G(M3) Ganglioside?

G(M3) Ganglioside is suspected in Renal glomerular disease, Sandhoff Disease, Nodular glomerulosclerosis, Diabetic Nephropathy, Diabetes, Fatty Streak, Arterial and other diseases in descending order of the highest number of associated sentences.

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No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with G(M3) Ganglioside

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with G(M3) Ganglioside?

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What functions are associated with G(M3) Ganglioside?


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What lipids are associated with G(M3) Ganglioside?

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What genes are associated with G(M3) Ganglioside?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with G(M3) Ganglioside?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with G(M3) Ganglioside

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Authors Title Published Journal PubMed Link
Niimi K et al. Impairment of neuropsychological behaviors in ganglioside GM3-knockout mice. 2011 Biochem. Biophys. Res. Commun. pmid:21333627
Miranda A et al. Cytofluorimetric evaluation of N-glycolylated GM3 ganglioside expression on murine leukocytes. 2011 Immunol. Lett. pmid:21324343
Garbuzova-Davis S et al. Blood-brain barrier impairment in an animal model of MPS III B. 2011 PLoS ONE pmid:21408219
Zarei M et al. Separation and identification of GM1b pathway Neu5Ac- and Neu5Gc gangliosides by on-line nanoHPLC-QToF MS and tandem MS: toward glycolipidomics screening of animal cell lines. 2010 Glycobiology pmid:19797321
Rusciani A et al. Elastin peptides signaling relies on neuraminidase-1-dependent lactosylceramide generation. 2010 PLoS ONE pmid:21103358
Spessott W et al. Defective GM3 synthesis in Cog2 null mutant CHO cells associates to mislocalization of lactosylceramide sialyltransferase in the Golgi complex. 2010 Neurochem. Res. pmid:21080064
Fernandez LE et al. NGcGM3 ganglioside: a privileged target for cancer vaccines. 2010 Clin. Dev. Immunol. pmid:21048926
Stamatos NM et al. LPS-induced cytokine production in human dendritic cells is regulated by sialidase activity. 2010 J. Leukoc. Biol. pmid:20826611
Nishimura B et al. The influences of sphingolipid metabolites on gentamicin-induced hair cell loss of the rat cochlea. 2010 Neurosci. Lett. pmid:20709153
Rojas-Garcia R et al. Bulbar involvement in patients with antiganglioside antibodies against NeuNAc(alpha2-3)Gal. 2010 J. Neurol. Neurosurg. Psychiatry pmid:19726412