|
baicalein |
baicalein is a lipid of Polyketides (PK) class. Baicalein is associated with abnormalities such as Neurodegenerative Disorders, Fibrillation, Hypertensive disease, Aortic coarctation and Coronary Occlusion. The involved functions are known as Anabolism, Polymerization, Process, inhibitors and Pathogenesis. Baicalein often locates in Membrane, Lipid Bilayers, soluble, Cell-Free System and Protoplasm. The associated genes with baicalein are P4HTM gene, BIRC5 gene, TSPO gene, SHOC2 gene and XIAP gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, iodoresiniferatoxin, Lipopolysaccharides and 17-octadecynoic acid. The related experimental models are Knock-out, Mouse Model and Parkinsonism, Experimental. |
1997 |
|
Wogonin |
Wogonin is a lipid of Polyketides (PK) class. Wogonin is associated with abnormalities such as Hyperlipidemia, Atherosclerosis, Inflammatory disorder, Dermatitis, Atopic and Ischemia. The involved functions are known as Inflammation, Regulation, luciferase activity, store-operated calcium entry and Transcriptional Activation. Wogonin often locates in Cytoplasmic matrix, Pore, Membrane, Protoplasm and Mitochondria. The associated genes with Wogonin are SGK1 gene, ORAI1 gene, STIM1 gene, P4HTM gene and BCL2 gene. |
732 |
|
Oroxylin A |
Oroxylin A is a lipid of Polyketides (PK) class. |
180 |
|
Fisetin |
Fisetin is a lipid of Polyketides (PK) class. Fisetin is associated with abnormalities such as Morphologically altered structure, PARKINSON DISEASE, LATE-ONSET, Tetanus, CNS disorder and Disintegration (morphologic abnormality). The involved functions are known as Autophagy, Apoptosis, Energy Metabolism, Acceleration and Anabolism. Fisetin often locates in Mitochondria, Cytoplasmic matrix, Extracellular, Cytoskeletal Filaments and Autophagic vacuole. The associated genes with Fisetin are SIRT1 gene, MAP1LC3A gene, TP53 gene, P4HTM gene and AURKB gene. The related lipids are Phosphatidylserines and Lipopolysaccharides. The related experimental models are Animal Cancer Model, Xenograft Model, Mouse Model, Cancer Model and Disease model. |
832 |
|
Juglanin |
Juglanin is a lipid of Polyketides (PK) class. |
18 |
|
licochalcone a |
licochalcone a is a lipid of Polyketides (PK) class. Licochalcone a is associated with abnormalities such as CLEFT LIP, CONGENITAL HEALED, Gastric ulcer, Keratoconjunctivitis Sicca, Inflammatory disorder and Leishmaniasis. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Germination, Cell Growth, Metabolic Inhibition and Respiratory Chain. Licochalcone a often locates in Cell surface, Plasma membrane, IkappaB kinase complex, Mitochondria and Membrane. The associated genes with licochalcone a are HM13 gene, Salmine, cytochrome c'', TNFRSF1A gene and RIPK1 gene. The related lipids are Promega. |
220 |
|
rottlerin |
Rottlerin is a lipid of Polyketides (PK) class. Rottlerin is associated with abnormalities such as PARAGANGLIOMAS 2, Hyperostosis, Diffuse Idiopathic Skeletal, Virus Diseases, Perisylvian syndrome and Autoimmune disease (systemic) NOS. The involved functions are known as Apoptosis, Regulation, Signal Transduction, inhibitors and Proteasome Inhibitors [MoA]. Rottlerin often locates in Clone, Membrane, Body tissue, Plasma membrane and soluble. The associated genes with Rottlerin are XIAP gene, GAPDH gene, ICAM1 gene, P4HTM gene and TNFSF10 gene. The related lipids are Promega, Fatty Acids, Sphingolipids, Lipopolysaccharides and Saponin. The related experimental models are Mouse Model, Xenograft Model and Cancer Model. |
1198 |
|
phloretin |
phloretin is a lipid of Polyketides (PK) class. Phloretin is associated with abnormalities such as Atherosclerosis, Diabetes Mellitus, Non-Insulin-Dependent, Alkalemia, Renal tubular disorder and pathologic fistula. The involved functions are known as Anabolism, glycosyltransferase activity, Biosynthetic Pathways, Localized desquamation and Biological Processes. Phloretin often locates in soluble, BL21, Cytoplasmic, Extracellular and Cytoplasm. The associated genes with phloretin are Homologous Gene, CD36 gene, Candidate Disease Gene, SLC33A1 gene and PAK1IP1 gene. The related lipids are Liposomes, Palmitates, Fatty Acids, Sterols and 6-ketocholestanol. The related experimental models are Knock-out. |
2367 |
|
naringenin |
naringenin is a lipid of Polyketides (PK) class. Naringenin is associated with abnormalities such as Dehydration, Papillon-Lefevre Disease, BOSLEY-SALIH-ALORAINY SYNDROME, Cardiovascular Diseases and Atherosclerosis. The involved functions are known as Pigmentation, Biosynthetic Pathways, metaplastic cell transformation, 4-coumarate-CoA ligase activity and Pigment. Naringenin often locates in Body tissue, Cell Wall, Membrane, Cytoplasmic matrix and Tissue membrane. The associated genes with naringenin are Genome, Genes, Regulator, Alleles, Homologous Gene and SPEN gene. The related lipids are Fatty Acids, Total cholesterol, Lipopolysaccharides, Oleates and Cholesterol, Dietary. The related experimental models are Knock-out and Mouse Model. |
2420 |
|
Alpinetin |
Alpinetin is a lipid of Polyketides (PK) class. |
72 |
|
emodin |
emodin is a lipid of Polyketides (PK) class. Emodin is associated with abnormalities such as Infection, Conjunctivitis, Vernal, Stevens-Johnson Syndrome, Conjunctival scar and Allergic Conjunctivitis. The involved functions are known as signaling cascade, Metabolic Inhibition, Cell Death, Phosphorylation and JNK Pathway. Emodin often locates in Membrane, Protoplasm, Mitochondria, Cytoplasmic matrix and soluble. The associated genes with emodin are cytochrome c'', UTS2 gene, TK Gene, Gene Clusters and CFC1 gene. The related lipids are Phosphatidylserines, Promega, Sphingolipids, Membrane Lipids and Palmitates. The related experimental models are Mouse Model and Transgenic Model. |
1742 |
|
doxorubicin |
Adriamycin is a lipid of Polyketides (PK) class. Adriamycin is associated with abnormalities such as Cardiomyopathies. The involved functions are known as Transcription, Genetic, Process, Drug effect disorder, Diastasis and Oxidation-Reduction. Adriamycin often locates in Muscle, Myocardium and Entire gastrointestinal tract. |
54913 |
|
(-)-Perillyl alcohol |
(-)-perillyl alcohol is a lipid of Prenol Lipids (PR) class. The involved functions are known as Cell Cycle Progression, Cell Cycle, Cell Proliferation, Apoptosis and Isoprenylation. (-)-perillyl alcohol often locates in Cytoplasm, Membrane and Plasma membrane. The associated genes with (-)-Perillyl alcohol are JUN gene, Candidate Disease Gene, IL24 gene, BCL2L1 gene and CFB gene. The related experimental models are Transgenic Model. |
299 |
|
2E,6E-farnesol |
2e,6e-farnesol is a lipid of Prenol Lipids (PR) class. 2e,6e-farnesol is associated with abnormalities such as Granulomatous Disease, Chronic, pathologic fistula and Cavitation. The involved functions are known as Regulation, Metabolic Inhibition, cholesterol biosynthetic process, Process and Transcription, Genetic. 2e,6e-farnesol often locates in Plasma membrane, Cytoplasmic matrix, cornified envelope, Epidermis and peroxisome. The associated genes with 2E,6E-farnesol are RAB3A gene, FOSL1 gene, CASP8AP2 gene, RCC1 gene and GALE gene. The related lipids are Sterols, Membrane Lipids and Steroids. |
1905 |
|
(e,z)-farnesol |
(e,z)-farnesol is a lipid of Prenol Lipids (PR) class. |
1183 |
|
(z,z)-farnesol |
(z,z)-farnesol is a lipid of Prenol Lipids (PR) class. |
1183 |
|
Levomenol |
Levomenol is a lipid of Prenol Lipids (PR) class. |
241 |
|
Parthenolide |
Parthenolide is a lipid of Prenol Lipids (PR) class. Parthenolide is associated with abnormalities such as Migraine Disorders, abnormal fragmented structure, Hyperostosis, Diffuse Idiopathic Skeletal, Consumption-archaic term for TB and Infection. The involved functions are known as Apoptosis, Cell Proliferation, Inflammation, pathologic cytolysis and Membrane Potentials. Parthenolide often locates in Mitochondria, Tissue membrane, Cytoplasmic matrix, Cytoplasm and Body tissue. The associated genes with Parthenolide are IGKJ1 gene, BCL2 gene, DDIT3 gene, Procaspase 7 and GAPDH gene. The related lipids are A(2)C. The related experimental models are Mouse Model, Xenograft Model, Breast Cancer Model and Cancer Model. |
925 |
|
Gossypol |
Gossypol is a lipid of Prenol Lipids (PR) class. Gossypol is associated with abnormalities such as Paralytic Ileus, PARKINSON DISEASE, LATE-ONSET, Fibrillation, Hepatic necrosis and Lymphopenia. The involved functions are known as Atrophic, Ulcer, Necrosis, Apoptosis and antagonists. Gossypol often locates in Mucous Membrane, Epithelium, Blood, Microsomes, Liver and Autophagic vacuole. The associated genes with Gossypol are BCL2A1 gene, BCL2 gene, Transgenes, IGH@ gene cluster and Bax protein (53-86). The related lipids are Promega, proteoliposomes, Phosphatidylserines and Liposomes. The related experimental models are Transgenic Model and Xenograft Model. |
2557 |
|
Thapsigargin |
Thapsigargin is a lipid of Prenol Lipids (PR) class. Thapsigargin is associated with abnormalities such as Impaired glucose tolerance, Obesity and Blood Pressure Disorders. The involved functions are known as Phosphorylation, establishment and maintenance of localization, Regulation, Metabolic Inhibition and Proteolysis. Thapsigargin often locates in Mouse Skin, Cytoplasm, Skin, Protoplasm and Mitochondria. The associated genes with Thapsigargin are ERBB4 gene, F11 gene, CA1 gene, TRNAP1 gene and HSPA5 gene. The related lipids are taurolithocholic acid 3-sulfate, Liposomes, Fatty Acids and stearylamine. The related experimental models are Mouse Model. |
8868 |
|
Geranylgeraniol |
Geranylgeraniol is a lipid of Prenol Lipids (PR) class. Geranylgeraniol is associated with abnormalities such as abnormal fragmented structure, Hyperostosis, Diffuse Idiopathic Skeletal and Tuberculosis. The involved functions are known as Positive Regulation of Apoptosis, Anabolism, Prenylation, Apoptosis and pathologic cytolysis. Geranylgeraniol often locates in Body tissue, Cytoplasmic matrix, Red Cell Ghost, Spindle and Nuclear lamin. The associated genes with Geranylgeraniol are MST1 gene, STN gene, UMOD gene, ABCA1 gene and RHOA gene. The related lipids are Sterols, Hydroxycholesterols, SK&F 104976 and 25-hydroxycholesterol. |
403 |
|
forskolin |
Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides. |
24755 |
|
Phorbol |
Phorbol is a lipid of Prenol Lipids (PR) class. Phorbol is associated with abnormalities such as furuncle, Infection, endothelial dysfunction, Morphologically altered structure and Acute erythroleukemia. The involved functions are known as Tyrosine Phosphorylation, Metabolic Inhibition, Transcription, Genetic, Protein Biosynthesis and Signal. Phorbol often locates in Tissue membrane, Membrane, Cell surface, soluble and Cytoplasmic Domain. The associated genes with Phorbol are STAT3 gene, JAK2 gene, JUN gene, PROC gene and MAPK8 gene. The related lipids are Lipopolysaccharides, Phosphatidylserines, Liposomes, Fatty Acids and Octanols. |
2082 |
|
phorbol 13-acetate 12-myristate |
Phorbol 13-acetate 12-myristate is a lipid of Prenol Lipids (PR) class. The involved functions are known as DNA Fragmentation, Phosphorylation and Irritation. Phorbol 13-acetate 12-myristate often locates in low-density lipoprotein particle. The associated genes with phorbol 13-acetate 12-myristate are FPR1 gene and ABCB1 gene. |
40921 |
|
Sphingosine 1-phosphate |
Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis. |
2005 |
|
sphingosylphosphorylcholine |
sphingosylphosphorylcholine is a lipid of Sphingolipids (SP) class. Sphingosylphosphorylcholine is associated with abnormalities such as Cerebral Vasospasm, Subarachnoid Hemorrhage, Atherosclerosis, Hypertensive disease and Niemann-Pick Diseases. The involved functions are known as MAP kinase kinase activity, JUN kinase activity, Phosphorylation, biphenyl synthase activity and Cell Death. Sphingosylphosphorylcholine often locates in Adipose tissue, Protoplasm, Body tissue, Membrane and Extracellular. The associated genes with sphingosylphosphorylcholine are UCN3 gene, MAPK9 gene, JUN gene, NAA50 gene and P4HTM gene. The related lipids are Lysophospholipids, lysophosphatidic acid, Lysophosphatidylcholines, Sphingolipids and Saponin. The related experimental models are Mouse Model. |
265 |
|
cholesterol |
cholesterol is a lipid of Sterol Lipids (ST) class. Cholesterol is associated with abnormalities such as Trypanosomiasis, Chagas Disease, Cleft Palate, Chondrodysplasia punctata 2, X-linked dominant and Child syndrome. The involved functions are known as Blood Circulation, Sterol Biosynthesis Pathway, Receptor Mediated Endocytosis, Methylation and Signal. Cholesterol often locates in Animal tissue, Blood, Membrane, Plasma membrane and peroxisome. The associated genes with cholesterol are MBD2 gene, SIM, SLC33A1 gene, Genome and NSDHL gene. The related lipids are Sterols, zymosterol, fecosterol, Total cholesterol and 7-dehydrocholesterol. The related experimental models are Mouse Model, Knock-out, Genetically Engineered Mouse and Disease model. |
98461 |