Disease MeSH term: Heart Failure

Possible associated with:

Structure name description Reference count
SCHEMBL105486 Kakonein is a lipid of Polyketides (PK) class. Kakonein is associated with abnormalities such as Fatty Liver, Chronic liver disease, Morphologically altered structure, Hypertensive disease and Cardiovascular Diseases. The involved functions are known as protein expression, Extravasation, Liver damage, mRNA Expression and cell activation. Kakonein often locates in Body tissue, Hepatic, Microvilli, Cytoplasm and Membrane. The associated genes with Kakonein are TJP1 gene, CD14 gene, iberiotoxin, AT-Rich Interactive Domain-Containing Protein 1A and NKS1 gene. The related lipids are dehydrosoyasaponin I and Steroids. The related experimental models are Knock-out. 1391
Glucaric acid Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out. 1814
Sphingosine 1-phosphate Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis. 2005
15-F2t-IsoP 15-f2t-isop is a lipid of Fatty Acyls (FA) class. 15-f2t-isop is associated with abnormalities such as Diabetes Mellitus, Acute coronary syndrome, Risk factor, cardiovascular, thrombocytosis and Chronic ischemic heart disease NOS. The involved functions are known as Anabolism, Inflammation, Lipid Peroxidation, Excretory function and Platelet Activation. The associated genes with 15-F2t-IsoP are PTGS2 gene. 2120
Dichloroacetic acid Dichloroacetic acid is a lipid of Fatty Acyls (FA) class. Dichloroacetic acid is associated with abnormalities such as Acidosis, Lactic, Metabolic Diseases, CLEFT LIP, CONGENITAL HEALED, Asthma and hyperthyroid. The involved functions are known as inhibitors, Chlorination, Metabolic Inhibition, Process and Sterility. Dichloroacetic acid often locates in Intestine - Large Intestine - Cecum (MMHCC), Mouse Liver, Back and Head. The associated genes with Dichloroacetic acid are GSTZ1 gene, PSMA5 gene and Maleylacetoacetate isomerase. The related lipids are Nonesterified Fatty Acids. 2361
Triolein Triolein is a lipid of Glycerolipids (GL) class. Triolein is associated with abnormalities such as Lymph fistula and Hyperlipidemia. The involved functions are known as Exocytosis, cholesterol transport and lipoprotein lipase activity. Triolein often locates in Mucous Membrane, Hepatic and Intestinal Mucosa. The related lipids are Cholesterol, Dietary. The related experimental models are Knock-out. 2752
6-aminohexanoic acid 6-aminohexanoic acid is a lipid of Fatty Acyls (FA) class. 6-aminohexanoic acid is associated with abnormalities such as Blood Clot, Myocardial Infarction, Cerebrovascular accident, Renal impairment and Scoliosis, unspecified. The involved functions are known as Fibrinolysis, Agent, Hemorrhage, plasminogen activation and inhibitors. 6-aminohexanoic acid often locates in Chest, Blood, Body tissue, peritoneal and Plasma membrane. The associated genes with 6-aminohexanoic acid are P4HTM gene, BSND gene, MTPN gene, NDUFS4 gene and Homologous Gene. The related lipids are Phosphatidylserines and Butyric Acid. 3685
alpha-linolenic acid Alpha-linolenic acid is a lipid of Fatty Acyls (FA) class. Alpha-linolenic acid is associated with abnormalities such as Coronary heart disease, abnormal fragmented structure, Arterial thrombosis and Subarachnoid Hemorrhage. The involved functions are known as Anabolism, Signal, Transcription, Genetic, Saturated and Regulation. Alpha-linolenic acid often locates in Blood, Body tissue, Plasma membrane, Hepatic and peroxisome. The associated genes with alpha-linolenic acid are FATE1 gene, volicitin, CYP2U1 gene, CYP1A2 gene and CYP2J2 gene. The related lipids are Fatty Acids, Dietary Fatty Acid, stearidonic acid and Fatty Acids, Nonesterified. 4231
4-hydroxynonenal 4-hydroxynonenal is a lipid of Fatty Acyls (FA) class. 4-hydroxynonenal is associated with abnormalities such as Chronic disease, Obesity, Diabetes, Acquired Immunodeficiency Syndrome and Lung diseases. The involved functions are known as protein expression, Glycolysis, mRNA Expression, Regulation and Mitochondrion in division. 4-hydroxynonenal often locates in Muscle, Mitochondria, Adipose tissue, Head and Mouse Muscle. The associated genes with 4-hydroxynonenal are STAT3 gene, SIRT1 gene, PGC gene, IL6 gene and cytochrome c''. The related lipids are Lipopolysaccharides, Lipid Peroxides, Promega, Membrane Lipids and oxidized lipid. The related experimental models are Mouse Model, Knock-out, Transgenic Model, Disease model and Rodent Model. 5685
Linoleic acid Linoleic acid is a lipid of Fatty Acyls (FA) class. Linoleic acid is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Metabolic syndrome, Obesity, Chronic Obstructive Airway Disease and Pneumonia. The involved functions are known as Insulin Resistance, Inflammation, Synthesis, Pathological accumulation of air in tissues and cytokine biosynthesis. The associated genes with Linoleic acid are TNF gene, CCL2 gene and TLR4 gene. The related lipids are palmitoleic acid, nervonic acid and Sphingolipids. 5699
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