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Nobiletin |
Nobiletin is a lipid of Polyketides (PK) class. Nobiletin is associated with abnormalities such as Hashimoto Disease, nervous system disorder, Dermatitis, Senile Plaques and Metabolic Diseases. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Signal Transduction, Biochemical Pathway, Phosphorylation and MAP kinase kinase activity. Nobiletin often locates in Extracellular, Protoplasm, Back, Mouse Skin and Skin - Epidermis (MMHCC). The associated genes with Nobiletin are MAP2K1 gene, PTGS2 gene, Amyloid beta-Protein Precursor, Candidate Disease Gene and BCL2 gene. The related lipids are Lipopolysaccharides and Sterols. The related experimental models are Mouse Model and Transgenic Model. |
550 |
|
naringenin |
naringenin is a lipid of Polyketides (PK) class. Naringenin is associated with abnormalities such as Dehydration, Papillon-Lefevre Disease, BOSLEY-SALIH-ALORAINY SYNDROME, Cardiovascular Diseases and Atherosclerosis. The involved functions are known as Pigmentation, Biosynthetic Pathways, metaplastic cell transformation, 4-coumarate-CoA ligase activity and Pigment. Naringenin often locates in Body tissue, Cell Wall, Membrane, Cytoplasmic matrix and Tissue membrane. The associated genes with naringenin are Genome, Genes, Regulator, Alleles, Homologous Gene and SPEN gene. The related lipids are Fatty Acids, Total cholesterol, Lipopolysaccharides, Oleates and Cholesterol, Dietary. The related experimental models are Knock-out and Mouse Model. |
2420 |
|
hesperetin |
Hesperetin is a lipid of Polyketides (PK) class. Hesperetin is associated with abnormalities such as Corn of toe, Ischemia, Osteoporosis, Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as conjugation, inhibitors, Process, mRNA Expression and Adjudication. Hesperetin often locates in Entire intestinal epithelium, Protoplasm, Membrane, Shoulder and Back. The associated genes with Hesperetin are ABCG2 gene, ABCC2 gene, FATE1 gene, ABCB1 gene and P-glycoprotein 2. |
801 |
|
Cholic acid |
Cholic acid is a lipid of Sterol Lipids (ST) class. Cholic acid is associated with abnormalities such as Cholestasis, Intrahepatic Cholestasis, Atherosclerosis, Diabetes and cholesterol gallstones. The involved functions are known as Homeostasis, Enterohepatic Circulation, Proliferation (morphologic abnormality), Process and Cell Proliferation. Cholic acid often locates in Hepatic, Cytoplasmic matrix, Membrane, Protoplasm and Tissue membrane. The associated genes with Cholic acid are CYP27A1 gene, ABCB11 gene, NR5A2 gene, SLC10A2 gene and SLC10A1 gene. The related lipids are ursocholic acid, Steroids, Cholestenes, Cholestanes and cholanic acid. |
3054 |
|
rottlerin |
Rottlerin is a lipid of Polyketides (PK) class. Rottlerin is associated with abnormalities such as PARAGANGLIOMAS 2, Hyperostosis, Diffuse Idiopathic Skeletal, Virus Diseases, Perisylvian syndrome and Autoimmune disease (systemic) NOS. The involved functions are known as Apoptosis, Regulation, Signal Transduction, inhibitors and Proteasome Inhibitors [MoA]. Rottlerin often locates in Clone, Membrane, Body tissue, Plasma membrane and soluble. The associated genes with Rottlerin are XIAP gene, GAPDH gene, ICAM1 gene, P4HTM gene and TNFSF10 gene. The related lipids are Promega, Fatty Acids, Sphingolipids, Lipopolysaccharides and Saponin. The related experimental models are Mouse Model, Xenograft Model and Cancer Model. |
1198 |
|
NSC5548 |
NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol. |
283 |
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hypericin |
hypericin is a lipid of Polyketides (PK) class. Hypericin is associated with abnormalities such as Dermatitis, Phototoxic, Dehydration, Photosensitization, Morphologically altered structure and Myocardial Infarction. The involved functions are known as Cell Cycle Checkpoints, Apoptosis, Acetylation, Cell Survival and Caspase Activation. Hypericin often locates in insoluble fraction, Cytoplasmic matrix, Protoplasm, Tissue membrane and Cytoplasm. The associated genes with hypericin are CDC37 gene, HSPA8 gene, RAF1 gene, cyclin H and FK228. The related lipids are Phosphatidylserines. |
1752 |
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Rhein |
Rhein is a lipid of Polyketides (PK) class. Rhein is associated with abnormalities such as Obesity, Non-alcoholic Fatty Liver Disease, Dyslipidemias, Fatty Liver and Degenerative polyarthritis. The involved functions are known as Adipogenesis, Insulin Resistance, luciferase activity, Transcription, Genetic and Inflammation. Rhein often locates in Hepatic, Brown Fat, Muscle, Mouse Liver and Mitochondria. The associated genes with Rhein are QRSL1 gene, Candidate Disease Gene, CFB gene, STAT6 gene and GATA3 gene. The related lipids are Fatty Acids. |
986 |
|
(+)-Camphor |
(+)-camphor is a lipid of Prenol Lipids (PR) class. (+)-camphor is associated with abnormalities such as Athetoid cerebral palsy. The involved functions are known as inhibitors, Synthesis, Feedback and Competitive inhibition. The associated genes with (+)-Camphor are 4S-limonene synthase. The related lipids are palmitoleic acid, pentadecanoic acid, stearic acid and erucic acid. |
3660 |
|
fumagillin |
Fumagillin is a lipid of Prenol Lipids (PR) class. Fumagillin is associated with abnormalities such as Atherosclerosis, Dentatorubral-Pallidoluysian Atrophy, Severe Combined Immunodeficiency, Immunologic Deficiency Syndromes and Arthritis. The involved functions are known as Gene Expression, Apoptosis, Angiogenic Process, Infiltration and Adverse effects. Fumagillin often locates in Endothelium, Body tissue, Blood, soluble and Protoplasm. The associated genes with fumagillin are HIST1H1C gene, RAC1 gene, c-myb Genes, METAP2 gene and NCKIPSD gene. The related lipids are helvolic acid, Butyrates and Butanols. The related experimental models are Mouse Model, Xenograft Model and Cancer Model. |
500 |