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Nobiletin |
Nobiletin is a lipid of Polyketides (PK) class. Nobiletin is associated with abnormalities such as Hashimoto Disease, nervous system disorder, Dermatitis, Senile Plaques and Metabolic Diseases. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Signal Transduction, Biochemical Pathway, Phosphorylation and MAP kinase kinase activity. Nobiletin often locates in Extracellular, Protoplasm, Back, Mouse Skin and Skin - Epidermis (MMHCC). The associated genes with Nobiletin are MAP2K1 gene, PTGS2 gene, Amyloid beta-Protein Precursor, Candidate Disease Gene and BCL2 gene. The related lipids are Lipopolysaccharides and Sterols. The related experimental models are Mouse Model and Transgenic Model. |
550 |
|
emodin |
emodin is a lipid of Polyketides (PK) class. Emodin is associated with abnormalities such as Infection, Conjunctivitis, Vernal, Stevens-Johnson Syndrome, Conjunctival scar and Allergic Conjunctivitis. The involved functions are known as signaling cascade, Metabolic Inhibition, Cell Death, Phosphorylation and JNK Pathway. Emodin often locates in Membrane, Protoplasm, Mitochondria, Cytoplasmic matrix and soluble. The associated genes with emodin are cytochrome c'', UTS2 gene, TK Gene, Gene Clusters and CFC1 gene. The related lipids are Phosphatidylserines, Promega, Sphingolipids, Membrane Lipids and Palmitates. The related experimental models are Mouse Model and Transgenic Model. |
1742 |
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doxorubicin |
Adriamycin is a lipid of Polyketides (PK) class. Adriamycin is associated with abnormalities such as Cardiomyopathies. The involved functions are known as Transcription, Genetic, Process, Drug effect disorder, Diastasis and Oxidation-Reduction. Adriamycin often locates in Muscle, Myocardium and Entire gastrointestinal tract. |
54913 |
|
fumagillin |
Fumagillin is a lipid of Prenol Lipids (PR) class. Fumagillin is associated with abnormalities such as Atherosclerosis, Dentatorubral-Pallidoluysian Atrophy, Severe Combined Immunodeficiency, Immunologic Deficiency Syndromes and Arthritis. The involved functions are known as Gene Expression, Apoptosis, Angiogenic Process, Infiltration and Adverse effects. Fumagillin often locates in Endothelium, Body tissue, Blood, soluble and Protoplasm. The associated genes with fumagillin are HIST1H1C gene, RAC1 gene, c-myb Genes, METAP2 gene and NCKIPSD gene. The related lipids are helvolic acid, Butyrates and Butanols. The related experimental models are Mouse Model, Xenograft Model and Cancer Model. |
500 |
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Gossypol |
Gossypol is a lipid of Prenol Lipids (PR) class. Gossypol is associated with abnormalities such as Paralytic Ileus, PARKINSON DISEASE, LATE-ONSET, Fibrillation, Hepatic necrosis and Lymphopenia. The involved functions are known as Atrophic, Ulcer, Necrosis, Apoptosis and antagonists. Gossypol often locates in Mucous Membrane, Epithelium, Blood, Microsomes, Liver and Autophagic vacuole. The associated genes with Gossypol are BCL2A1 gene, BCL2 gene, Transgenes, IGH@ gene cluster and Bax protein (53-86). The related lipids are Promega, proteoliposomes, Phosphatidylserines and Liposomes. The related experimental models are Transgenic Model and Xenograft Model. |
2557 |
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forskolin |
Forskolin is a lipid of Prenol Lipids (PR) class. Forskolin is associated with abnormalities such as Cholestasis, Vocal cord dysfunction familial, Hypothyroidism, Renal tubular disorder and Disintegration (morphologic abnormality). The involved functions are known as Cell Proliferation, Anabolism, mRNA Expression, Agent and Signal. Forskolin often locates in Extracellular, Body tissue, Skin, Tissue membrane and Membrane. The associated genes with forskolin are P4HTM gene, SLC33A1 gene, NR1I2 gene, Genes, Reporter and CYP3A gene. The related lipids are Steroids, steroid sulfate, Fatty Acids, LYSO-PC and Lipopolysaccharides. |
24755 |
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phorbol 13-acetate 12-myristate |
Phorbol 13-acetate 12-myristate is a lipid of Prenol Lipids (PR) class. The involved functions are known as DNA Fragmentation, Phosphorylation and Irritation. Phorbol 13-acetate 12-myristate often locates in low-density lipoprotein particle. The associated genes with phorbol 13-acetate 12-myristate are FPR1 gene and ABCB1 gene. |
40921 |
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Sphingosine 1-phosphate |
Sphingosine 1-phosphate is a lipid of Sphingolipids (SP) class. Sphingosine 1-phosphate is associated with abnormalities such as Infection, Painful Bladder Syndrome, Atherosclerosis, Hyperglycemia and Rheumatoid Arthritis. The involved functions are known as Phosphorylation, Regulation, enzyme activity, Energy Absorption and Vascular Permeability. Sphingosine 1-phosphate often locates in Endothelium, Tissue membrane, Vascular System, Protoplasm and Microfilaments. The associated genes with Sphingosine 1-phosphate are MBTPS1 gene, FBXL15 gene, TEK gene, NTRK1 gene and Gene Family. The related lipids are Promega, Lipopolysaccharides, lysophosphatidic acid, Lysophosphatidylcholines and Lysophospholipids. The related experimental models are Knock-out, Mouse Model, Transgenic Model, Disease model and Experimental Autoimmune Encephalomyelitis. |
2005 |
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cholesterol |
cholesterol is a lipid of Sterol Lipids (ST) class. Cholesterol is associated with abnormalities such as Trypanosomiasis, Chagas Disease, Cleft Palate, Chondrodysplasia punctata 2, X-linked dominant and Child syndrome. The involved functions are known as Blood Circulation, Sterol Biosynthesis Pathway, Receptor Mediated Endocytosis, Methylation and Signal. Cholesterol often locates in Animal tissue, Blood, Membrane, Plasma membrane and peroxisome. The associated genes with cholesterol are MBD2 gene, SIM, SLC33A1 gene, Genome and NSDHL gene. The related lipids are Sterols, zymosterol, fecosterol, Total cholesterol and 7-dehydrocholesterol. The related experimental models are Mouse Model, Knock-out, Genetically Engineered Mouse and Disease model. |
98461 |