Pikromycin

Pikromycin is a lipid of Polyketides (PK) class. The involved functions are known as Anabolism, Process, Cytokinesis, Mutation and Biochemical Pathway. Pikromycin often locates in soluble. The associated genes with Pikromycin are SLC7A1 gene, Homologous Gene, Gene Clusters, Polypeptides and THEMIS gene.

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Introduction

To understand associated biological information of Pikromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pikromycin?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Pikromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pikromycin?

Related references are published most in these journals:

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What functions are associated with Pikromycin?


Related references are published most in these journals:

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What lipids are associated with Pikromycin?

There are no associated biomedical information in the current reference collection.

What genes are associated with Pikromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Pikromycin?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Pikromycin

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Authors Title Published Journal PubMed Link
Kittendorf JD and Sherman DH The methymycin/pikromycin pathway: a model for metabolic diversity in natural product biosynthesis. 2009 Bioorg. Med. Chem. pmid:19027305
Maharjan S et al. Identification and functional characterization of an afsR homolog regulatory gene from Streptomyces venezuelae ATCC 15439. 2009 J. Microbiol. Biotechnol. pmid:19307759
Yan J et al. Functional dissection of a multimodular polypeptide of the pikromycin polyketide synthase into monomodules by using a matched pair of heterologous docking domains. 2009 Chembiochem pmid:19437523
Lopanik NB et al. In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont. 2008 Chem. Biol. pmid:19022178
Maharjan S et al. Heterologous expression of metK1-sp and afsR-sp in Streptomyces venezuelae for the production of pikromycin. 2008 Biotechnol. Lett. pmid:18421418
Gupta S et al. Generation of novel pikromycin antibiotic products through mutasynthesis. 2008 Chembiochem pmid:18512859
Kittendorf JD et al. Interrogating the molecular basis for multiple macrolactone ring formation by the pikromycin polyketide synthase. 2007 Chem. Biol. pmid:17719493
Giraldes JW et al. Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels. 2006 Nat. Chem. Biol. pmid:16969373
O'Connor SE Cyclization of natural products. 2006 Nat. Chem. Biol. pmid:16983382
Venkatraman L et al. Total synthesis of narbonolide and biotransformation to pikromycin. 2006 J. Org. Chem. pmid:17168607